Microglial autophagy in neurogenesis:a new player in Alzheimer's disease  

作　　者：Xin Tang Aarti Nagayach Chenran Wang 

机构地区：[1]Department of Cancer Biology,University of Cincinnati College of Medicine,Cincinnati,OH,USA

出　　处：《Neural Regeneration Research》2024年第12期2573-2574,共2页中国神经再生研究（英文版）

基　　金：supported by NIHR01 NS103981 and R01CA273586 to CW。

摘　　要：While extensive studies have illuminated the impact of Alzheimer's disease(AD) on neuronal survival,there is growing evidence that abnormal postnatal neurogenesis in early AD brains contributes to disease progression.Postnatal neurogenesis serves as a mechanism to replace dead or damaged neurons.New neurons generated from neural stem cells(NSCs) in the subgranular zone(SGZ) of the dentate gyrus integrate into the existing hippocampal circuit.

关 键 词：ALZHEIMER replace INTEGRATE 

分 类 号：R749.16[医药卫生—神经病学与精神病学]