金丝小枣全枣、枣皮、枣肉黄酮提取物的抗氧化活性和免疫活性  

Antioxidant and Immune Activity of Total Flavonoids Extracts from the Whole,Skin and Flesh of Ziziphus jujuba

作　　者：师仁丽 刘欣宜 张彩玉 徐志悦 桑亚新[1] 于文龙[1] 王向红[1] SHI Reni;LIU Xinyi;ZHANG Caiyu;XU Zhiyue;SANG Yaxin;YU Wenong;WANG Xianghong(College of Food Science and Technology,Hebei Agricultural University,Baoding 071000,Hebei,China)

机构地区：[1]河北农业大学食品科技学院,河北保定071000

出　　处：《食品研究与开发》2024年第7期103-108,共6页Food Research and Development

基　　金：河北农业大学引进人才科研专项(YJ2020024);“十四五”国家重点研发计划项目(2022YFD1600400)。

摘　　要：以金丝小枣为研究对象,分别测定金丝小枣全枣、枣皮、枣肉的黄酮提取物对DPPH·、ABTS+·、·OH清除能力和总还原力,并利用刀豆蛋白A(concanavalin A,ConA)和脂多糖(lipopolysaccharide,LPS)分别诱导小鼠脾脏T淋巴细胞和B淋巴细胞增殖反应,探究金丝小枣的全枣、枣皮、枣肉的黄酮提取物的免疫活性。试验结果表明:金丝小枣全枣、枣皮、枣肉黄酮抗氧化活性和免疫活性存在差异,枣皮黄酮的抗氧化活性和免疫活性最强,枣肉黄酮提取物的抗氧化活性和免疫活性最弱,但全枣、枣皮、枣肉黄酮提取物对DPPH·和·OH的清除活性高于VC,且全枣、枣皮、枣肉黄酮提取物对小鼠脾脏T淋巴细胞、B淋巴细胞的增殖均具有促进作用。In this study,the scavenging capacity and total reducing capacity of the total flavonoid extracts of the whole,skin and flesh of Ziziphus jujuba on DPPH·,ABTS+·,·OH were measured.Additionally,mouse splenic T lymphocytes and B lymphocytes were induced separately using concanavalin A(ConA)and lipopoly-saccharide(LPS)to investigate the immunomodulatory activities of the flavonoid extracts.The results indi-cated variations in the antioxidant and immune activities among the total flavonoids from the whole date,the skin and the flesh of Ziziphus jujuba.The total flavonoids from the skin of the jujube had the strongest antioxi-dant and immune activities,while the total flavonoids from the flesh of the jujube had the weakest antioxidant and immune activities.However,all three jujube parts showed higher scavenging activities against DPPH·and·OH radicals compared to vitamin C.The total flavone extracts from whole jujube,jujube skin and jujube flesh could promote the proliferation of mouse splenic T lymphocytes and B lymphocytes.

关 键 词：金丝小枣 黄酮 提取 抗氧化活性 免疫活性 

分 类 号：TS255.1[轻工技术与工程—农产品加工及贮藏工程]