Research progress on the electrophysiological indicators to predict the efficacy of vagus nerve stimulation for drug-refractory epilepsy  

作　　者：Guangli Li Zhenguang Li Yingting Liu 

机构地区：[1]Hunan University of Chinese Medicine,Changsha,410208,Hunan Province,China [2]Epilepsy Center of Brain Hospital of Hunan Province,Changsha,410007,Hunan Province,China

出　　处：《Acta Epileptologica》2024年第1期14-20,共7页癫痫学报（英文）

摘　　要：Vagus nerve stimulation(VNS)is an important treatment option for drug-refractory epilepsy(DRE),with well-established efficacy and safety in clinical practice for more than 20 years.However,it is very difficult to find the optimal electrophysiological indicators for the effectiveness of VNS on DRE because the mechanism of action is unknown.In this review,we provide an update of the potential applications of VNS outcomes in patients with drug-resistant epilepsy.Electroencephalographic(EEG)activity,event-related potentials,EEG synchronization levels,magnetoencephalographic,laryngeal muscle evoked potentials,and heart rate variability are potential biomarkers for VNS outcomes in people with DRE.

关 键 词：ELECTROPHYSIOLOGY Vagus nerve stimulation Drug-refractory epilepsy EFFICACY Predictive indicators ELECTROENCEPHALOGRAM Event-related potential MAGNETOENCEPHALOGRAPHY Aryngeal muscle evoked potential Heart rate variability 

分 类 号：R742.1[医药卫生—神经病学与精神病学]