Endoplasmic reticulum stress improved chicken tenderness,promoted apoptosis and autophagy during postmortem ageing  

作　　者：Yuwei Chai Lin Chen Shuya Xiang Linxuan Wu Xuebo Liu Jun Luo Xianchao Feng 

机构地区：[1]College of Food Science and Engineering,Northwest A&F University,Yangling 712100,China [2]College of Animal Science and Technology,Northwest A&F University,Yangling 712100,China

出　　处：《Food Science and Human Wellness》2024年第4期2141-2151,共11页食品科学与人类健康（英文）

基　　金：supported by the National Natural Science Foundation of China(G32072142,31972099)。

摘　　要：In this study,endoplasmic reticulum(ER)stress inducer tunicamycin(TM)and inhibitor 4-phenylbutyric acid(4-PBA)were used to treat postmortem chicken breast muscle to investigate changes in tenderness and effects on apoptosis and autophagy during 5 days ageing.TM-induced ER stress reduced shear force,enhanced myofibril fragmentation index(MFI),disrupted myofibril structure,increased desmin degradation,and activatedμ-calpain and caspase-12.In addition,TM-induced ER stress increased the expression of Bax,Bim,and cytochrome c,and decreased the expression of Bcl-x L.Furthermore,TM-induced ER stress improved the conversion of LC3I to LC3II,raised the expression of Beclin-1,and decreased the expression of p62,PI3K,and m TOR.The opposite results were observed after 4-PBA treatment.These results suggested that ER stress could improve chicken tenderness,promote apoptosis and autophagy during chicken postmortem ageing.

关 键 词：Endoplasmic reticulum stress TENDERNESS APOPTOSIS AUTOPHAGY CHICKEN 

分 类 号：TS251.55[轻工技术与工程—农产品加工及贮藏工程]