Shedding light on gene therapy of Parkinson’s disease in non-human primates  

作　　者：Xunyi Yan Xin Jin 

机构地区：[1]New Cornerstone Science Laboratory,Center for Motor Control and Disease,Key Laboratory of Brain Functional Genomics,East China Normal University,3663 North Zhongshan Road,Shanghai 200062,China [2]NYU–ECNU Institute of Brain and Cognitive Science,New York University Shanghai,3663 North Zhongshan Road,Shanghai 200062,China

出　　处：《The Innovation》2024年第2期15-16,共2页创新（英文）

摘　　要：Parkinson’s disease(PD)is a progressive neurodegeneration disease initially described by James Parkinson.It is typically diagnosed based on clinical features such as bradykinesia,resting tremor,rigidity,and,in later stages,postural instability.Epidemiologically,the prevalence of PD ranges from 5 to over 35 cases per 100,000 population,with the majority affecting individuals aged 50 years or older.The risk increases with age,particularly in males.Various factors,including genetics,lifestyle,specific environmental influences,and geometry,contribute to the disease.

关 键 词：CLINICAL RIGIDITY initially 

分 类 号：R742.5[医药卫生—神经病学与精神病学]