Sex-dependent alterations in extracellular vesicles linking chronic spinal cord injury to brain neuroinflammation and neurodegeneration  

作　　者：Yun Li Junfang Wu 

机构地区：[1]Department of Anesthesiology&Shock,Trauma and Anesthesiology Research(STAR)Center,University of Maryland School of Medicine,Baltimore,MD,USA

出　　处：《Neural Regeneration Research》2025年第2期483-484,共2页中国神经再生研究（英文版）

基　　金：supported by NIH funding(RF1NS110637,2RF1NS094527,R01NS110635)to JW.

摘　　要：Traumatic spinal cord injury(SCI)is a devastating exogenous injury with long-lasting consequences and a leading cause of death and disability worldwide.Advances in assistive technology,rehabilitative interventions,and the ability to identify and intervene in secondary conditions have significantly increased the long-term survival rate of SCI patients,with some people even living well into their seventh or eighth decade.These survival changes have led neurotrauma researchers to examine how SCI interacts with brain aging.Public health and epidemiological data showed that patients with long-term SCI can have a lower life expectancy and quality of life,along with a higher risk of comorbidities and complications.

关 键 词：alterations INFLAMMATION INJURY 

分 类 号：R651.2[医药卫生—外科学]