急性髓系白血病患者情绪状态与预后的关系及影响因素分析  

Analysis of the relationship between emotional health and prognosis of patients with acute myeloid leukemia and its influencing factors

作　　者：周立群[1] 李静[1] ZHOU Liqun;LI Jing(Wuhan University Central South Hospital,Wuhan 430071,China)

机构地区：[1]武汉大学中南医院,武汉430071

出　　处：《国际精神病学杂志》2024年第2期533-538,共6页Journal Of International Psychiatry

摘　　要：目的探究急性髓系白血病(Acute myeloid leukemia,AML)患者情绪健康与预后的关系及分析影响因素。方法选取2021年9月~2022年9月本院收治的98例AML患者临床资料开展回顾性分析,通过量表评估患者情绪状况(焦虑与抑郁)与观察患者预后情况,分析情绪健康与预后相关性,并通过二元Logistic回归分析情绪健康影响因素。结果经临床评估结果显示,98例AML患者中存在抑郁76例,占比77.55%,存在焦虑80例,占比81.63%。所有患者随访1年显示预后良好82例(83.67%)、预后不良16例(16.33%)。且焦虑组预后良好率均低于无焦虑组,抑郁组预后良好率均低于无抑郁组(P<0.05)。Spearman相关分析显示,抑郁、焦虑均与预后呈负相关(r=-0.238、-0.210、P<0.05)。二元Logistic回归分析显示,职业状况(无业或退休)、文化程度(初中及以下)、家庭人均月收入(≤4000元)、性格(内向型)、疾病了解程度(不了解)均是焦虑或抑郁发生的危险因素(P<0.05)。结论AML患者多存在负性情绪,且负性情绪与患者预后状况存在相关,职业状况(无业或退休)、文化程度(初中及以下)、家庭人月均收入(≤4000元)、性格(内向型)、疾病了解程度(不了解)均是负性情绪的危险因素。Objective To explore the relationship between emotional health and prognosis of patients with acute myeloid leukemia(Acute myeloid leukemia AML)and analyze the influencing factors.Methods The clinical data of 98 AML patients admitted to our hospital from September 2021 to September 2022 were analyzed retrospectively.The emotional health status(anxiety and depression)of patients was evaluated by scale and the prognosis was observed.The correlation between emotional health and prognosis was analyzed,and the influencing factors of emotional health were analyzed by binary Logistic regression.Results According to the clinical evaluation,there were 76 cases of depression,accounting for 77.55%,and 80 cases of anxiety,accounting for 81.63%.Follow-up for one year showed that 82 cases(83.67%)had good prognosis and 16 cases(16.33%)had poor prognosis.The good prognosis rate of anxiety group was lower than that of non-anxiety group,and the good prognosis rate of depression group was lower than that of non-depression group(P<0.05).The spearman rank correlation coefficient is show that depression and anxiety were negatively correlated with prognosis(r=-0.238,-0.210,P<0.05).Logistic regression analysis showed that occupational status(unemployed or retired),education level(junior high school or below),average monthly income of family members(≤4000 yuan),personality(introversion)and degree of disease understanding(ignorance)were all risk factors for anxiety or depression(P<0.05).Conclusion Most patients with AML have negative emotions,and negative emotions are related to the prognosis of patients after treatment.Occupational status(unemployed or retired),education level(junior high school or below),monthly income of family members(≤4000 yuan),personality(introversion)and degree of understanding of diseases are all risk factors of negative emotions.

关 键 词：急性髓系白血病 情绪健康 预后 相关 影响因素 

分 类 号：R749[医药卫生—神经病学与精神病学]