畜禽血液外泌体功能及其资源开发研究进展  

Progress on the Function and Resource Development of Livestock and Poultry Blood Exosomes

作　　者：徐荣鹭 麦籍文 石雨薇 曹锦轩 张婵[1] 杨鑫垚 王雪儿 吴世翔 王颖[1] XU Ronglu;MAI Jiwen;SHI Yuwei;CAO Jinxuan;ZHANG Chan;YANG Xinyao;WANG Xue’er;WU Shixiang;WANG Ying(Key Laboratory of Geriatric Nutrition and Health,Ministry of Education,College of Food and Health,Beijing Technology and Business University,Beijing 100048,China)

机构地区：[1]北京工商大学食品与健康学院,老年营养与健康教育部重点实验室,北京100048

出　　处：《肉类研究》2024年第3期70-77,共8页Meat Research

基　　金：“十四五”国家重点研发计划重点专项(2023YFF1103900);国家自然科学基金面上项目(32372248);北京工商大学大学生创新训练项目(X202410011012);北京市教学发展研究课题项目(GJ2023016);北京工商大学教改项目(jg235108)。

摘　　要：我国畜禽血液资源十分丰富,目前血液蛋白精深加工、血液蛋白活性肽酶解、氯化血红素制备等工作已取得明显成效。近年来,血液外泌体作为一类新型功能性成分,已被证明具有多种功能活性,在食品营养补充剂方面具有极强的开发潜力。然而,血液外泌体的基础研究还处于起步阶段。为了未来更好地对血液外泌体进行有效资源开发,本文对其结构与化学组成进行概述,回顾血液外泌体功能活性的近年研究进展,综述不同提取、保存方法对血液外泌体活性的影响,对血液外泌体未来潜在的生产应用进行展望,旨在为畜禽血液资源挖掘、血液外泌体的进一步开发及应用提供思路。There are abundant blood resources of livestock and poultry in our country.At present,remarkable results have been achieved in the deep processing of blood proteins,the enzymatic hydrolysis of blood proteins for the production of active peptides,and the preparation of hemin chloride.In recent years,blood exosomes,as a new class of functional ingredients,have been shown to have a variety of functional activities,and have great potential in the development of nutritional food supplements.However,basic research on blood exosomes is still in its infancy.In order to develop blood exosomes effectively in the future,this paper summarizes the structure and chemical composition of blood exosomes,reviews the recent progress research on the functional activities of blood exosomes and the effects of different extraction and preservation methods on them,and discusses future prospects for the production and application of blood exosomes.This paper aims to provide ideas for the mining of livestock and poultry blood resources and the further development and application of blood exosomes.

关 键 词：畜禽血液 血液深加工 血液外泌体 功能活性 资源挖掘 

分 类 号：TS251.2[轻工技术与工程—农产品加工及贮藏工程]