Regulation of sleep by astrocytes in the hypothalamic ventrolateral preoptic nucleus  

作　　者：Jae-Hong Kim Ruqayya Afridi Il-Sung Jang Maan Gee Lee Kyoungho Suk 

机构地区：[1]Brain Korea 21 four KNU Convergence Educational Program of Biomedical Sciences for Creative Future Talents,School of Medicine,Kyungpook National University,Daegu,Republic of Korea [2]Department of Pharmacology,School of Medicine,Kyungpook National University,Daegu,Republic of Korea [3]Department of Pharmacology,School of Dentistry,Kyungpook National University,Daegu,Republic of Korea [4]Brain Science&Engineering Institute,Kyungpook National University,Daegu,Republic of Korea

出　　处：《Neural Regeneration Research》2025年第4期1098-1100,共3页中国神经再生研究（英文版）

基　　金：supported by a National Research Foundation of Korea(NRF)grant funded by the Korean government(2017R1A5A2015391 and 2020M3E5D9079764)(to KS).

摘　　要：Astrocytes are functionally dynamic cells that support neurons in multiple ways throughout an organism’s lifespan.The astrocytic regulation of neuronal activity has been increasingly recognized in recent years.Astrocytes are now recognized as playing a more complex role than mere bystanders in the central nervous system.However,their role in regulating the sleep neurocircuitry is not well understood.From this perspective,we highlight the role of astrocytes in sleep modulation,with a particular focus on regulatory mechanisms related to the ventrolateral preoptic nucleus(VLPO)of the hypothalamus.We briefly discuss recent literature reporting the role of VLPO astrocytes in regulating sleep-associated behaviors.

关 键 词：SLEEP ventrolateral ASTROCYTES 

分 类 号：R740[医药卫生—神经病学与精神病学]