Microglia in drug addiction:A perspective from neuroimmunopharmacology  

作　　者：Cong Lin Xiaohui Wang 

机构地区：[1]Laboratory of Chemical Biology,Changchun Institute of Applied Chemistry,Chinese Academy of Sciences,Changchun,Jilin 130022,China [2]Beijing National Laboratory for Molecular Sciences,Beijing 100190,China [3]School of Applied Chemistry and Engineering,University of Science and Technology of China,Hefei,Anhui 230026,China

出　　处：《Zoological Research》2024年第3期704-706,共3页动物学研究（英文）

基　　金：supported by the STI2030-Major Projects(2021ZD0203000(2021ZD0203003));National Science Foundation of China(22207105);Beijing National Laboratory for Molecular Sciences(BNLMS202108);Chinese Academy of Sciences Pioneer Hundred Talents Program。

摘　　要：Drug addiction refers to a state of dependence that arises from habitual drug intake and can result in specific withdrawal symptoms upon cessation.The most commonly abused substances include psychostimulants,cannabinoids,and opioids.When drugs are consumed,they stimulate the release of dopamine,a neurotransmitter crucial for the pleasure and reward centers of the brain.With repeated drug use,the brain undergoes various changes,leading to tolerance,dependence,and addiction(Lüscher et al.,2020).The mechanisms involved in drug addiction are highly complex and involve diverse cell types within the brain.

关 键 词：ADDICTION DRUGS INTAKE 

分 类 号：R749.61[医药卫生—神经病学与精神病学]