可逆热致变色纳米微胶囊材料在肿瘤光热治疗法中的应用  

Application of Reversible Thermochromic Nanocapsules in Photothermal Therapy of Tumor

作　　者：黄少波 易耀辉 张玄 陈伊雪 吴颖茵 佘文杰 陈嘉霖 邵友元 HUANG Shaobo;YI Yaohui;ZHANG Xuan;CHEN Yixue;WU Yingyin;SHE Wenjie;CHEN Jialin;SHAO Youyuan(College of Chemical Engineering and Energy Technology,Dongguan University of Technology,Dongguan 523808,China)

机构地区：[1]东莞理工学院化学工程与能源技术学院,广东东莞523808

出　　处：《东莞理工学院学报》2024年第3期73-80,共8页Journal of Dongguan University of Technology

基　　金：广东省工业高新技术项目(2017A010104014);东莞市社会科技发展项目(2014108101038);2023年(国家级)大学生创新创业训练计划项目(202311819016);东莞理工学院2020级应用化学专业卓越工程师导师制项目。

摘　　要：光热治疗法是当今治疗肿瘤的一项新技术。综述了纳米微胶囊在肿瘤光热治疗法中的应用及前景,阐述了肿瘤光热治疗法的治疗机理和不同光吸收材料的优缺点,总结了纳米微胶囊的基本生产工艺特点,提出了一种未来用于肿瘤光热治疗法中的可逆热致变色纳米微胶囊材料的制备新工艺和光热治疗法中所使用的可逆热致变色材料存在光热转化效率低、成本高等关键技术瓶颈的解决途径。Photothermal therapy is a new technology in the treatment of tumor.This paper reviews the application and prospect of nano-microcapsules in tumor photothermal therapy,and expounds the therapeutic mechanism of tumor photothermal therapy and the advantages and disadvantages of different light-absorbing materials,and summarizes the basic production process characteristics of nano microcapsules.On this basis,it proposes a new process for future preparation of reversible thermochromic nanocapsule materials in tumor photothermal treatment,and looks forward to the solutions to the key technical bottlenecks of low photothermal conversion efficiency and high cost of reversible thermochromic materials used in photothermal therapy.

关 键 词：微胶囊 纳米材料 壳聚糖 可逆热致变色材料 光热治疗法 

分 类 号：R730.5[医药卫生—肿瘤]