Rapamycin restores CD4^(+)T cell subsets imbalance in Graves' ophthalmopathy mice model  

作　　者：张萌 ZHANG Meng(Dept Endocrinol,1st Affil Hosp,Xi'an Jiaotong Univ,Xi'an 710061)

机构地区：[1]Dept Endocrinol,1st Affil Hosp,Xi'an Jiaotong Univ,Xi'an 710061

出　　处：《China Medical Abstracts(Internal Medicine)》2024年第1期29-30,共2页中国医学文摘（内科学分册（英文版）

摘　　要：Objective To study the effect of rapamycin on the disorder of CD4^(+)T cell subsets in Graves’ophthalmopathy (GO) mice,as well as the ophthalmopathy and hyperthyroidism phenotype,and to provide new possibilities for the treatment of GO.Methods 6-8weeks old female Balb/c mice were injected intramuscularly with adenovirus expressing the A-subunit of TSHR(A-sub-Ad) 9 times.Rapamycin was given by embedding in the feed (14 ppm).

关 键 词：GRAVES RAPAMYCIN EXPRESSING 

分 类 号：R96[医药卫生—药理学]