Comprehensive characterization of cell disulfidptosis in human cancers:An integrated pan-cancer analysis  

作　　者：Guo Zhao Yale Jiang Yuning Wang Shuhang Wang Ning Li 

机构地区：[1]Clinical Trial Center,National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital,Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing 100021,China

出　　处：《Genes & Diseases》2024年第4期5-8,共4页基因与疾病（英文）

基　　金：supported by the National Natural Science Foundation of China(No.82272951,82272953);Beijing Municipal Health Commission(Beijing Demonstration Research Ward BCRW20200303);Chinese Academy of Medical Sciences(No.2022-I2M-C&T-B-070).

摘　　要：Excessive accumulation of disulfide molecules,like cystine,can induce disulfide stress and high toxicity in cells,but the reduced form of nicotinamide adenine dinucleotide phosphate can reverse this process and mitigate disulfide stress.

关 键 词：DISULFIDE CANCER CHARACTERIZATION 

分 类 号：R730.2[医药卫生—肿瘤]