Long non-coding RNA BANCR promotes pancreatic cancer lymphangiogenesis and lymphatic metastasis by regulating the HIF-1α/VEGF-C/VEGFR-3 pathway via miR-143-5p  

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作  者:Shaolong Hao Yu Ji Weixuan Pan Hao Sun Fang Nie Jonathan Ray Warren Yuchuan Ding Wei Han 

机构地区:[1]Department of General Surgery,Beijing Luhe Hospital,Capital Medical University,Tongzhou,Beijing 101149,China [2]Department of Central Laboratory,Beijing Luhe Hospital,Capital Medical University,Tongzhou,Beijing 101149,China [3]Department of Neurosurgery,Wayne State University School of Medicine,John D.Dingell VA Medical Center,Detroit,MI 48201,USA

出  处:《Genes & Diseases》2024年第4期57-60,共4页基因与疾病(英文)

基  金:supported by the Capital Health Development Scientific Research Project(China)(No.2022-2-7081);Beijing Natural Science Foundation(China)(No.7234377);Science and Technology Plan Project of Tongzhou District,Beijing,China(No.KJ2022CX016).

摘  要:Pancreatic cancer is one of the most aggressive malignant tumors of the digestive system.Lymph node metastasis(LNM),as the main way of invasion and metastasis,can occur in the early stage of pancreatic cancer and be considered the most important factor affecting the clinical treatment and prognosis of patients with pancreatic cancer.

关 键 词:METASTASIS cancer INVASION 

分 类 号:R735.9[医药卫生—肿瘤]

 

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