自身免疫性小脑共济失调的诊治  

Diagnosis and treatment of autoimmune cerebellar ataxia

作　　者：关鸿志[1] Guan Hongzhi(Department of Neurology,Peking Union Medical College Hospital,Chinese Academy of Medical Sciences,Beijing 100730,China)

机构地区：[1]中国医学科学院北京协和医学院北京协和医院神经科,北京100730

出　　处：《中华神经科杂志》2024年第6期642-648,共7页Chinese Journal of Neurology

基　　金：北京协和医院中央高水平医院临床科研专项(2022-PUMCH-B-120)。

摘　　要：自身免疫性小脑共济失调是一种罕见的神经免疫病,是散发性共济失调重要的可治病因。近年来,一系列新型抗小脑抗体被陆续发现,相关诊断标准获得更新,基于中国患者的临床研究结果为该病的病因分类提供了新的依据。虽然多数患者对免疫治疗有反应,但改善患者的长期预后需要我们去探索更优的治疗策略。Autoimmune cerebellar ataxia(ACA)is a rare neuroimmune disease and a treatable cause of sporadic ataxia.In recent years,a series of new autoantibodies against cerebellum have been discovered,and the relevant diagnostic standards have been updated.Based on the clinical research results of Chinese patients with ACA,new data have been provided for the etiology classification of ACA.Although most patients respond to immunotherapy,improving long-term prognosis requires better treatment strategies.

关 键 词：自身免疫 共济失调 诊断 治疗 

分 类 号：R744.7[医药卫生—神经病学与精神病学]