桑蚕蛋白复合粉抗运动疲劳功效研究  

Anti-exercise fatigue effects of silkworm protein complex powder

作　　者：洪伟皓 栾一胜 马艺璇 熊莹喆 张冰 HONG Weihao;LUAN Yisheng;MA Yixuan;XIONG Yingzhe;ZHANG Bing(Division of Sports Science and Physical Education,Tsinghua University,Beijing 100081;School of Physical Education,Central China Normal University,Wuhan 430079)

机构地区：[1]清华大学体育部体育与健康科学研究中心,北京100081 [2]华中师范大学体育学院,武汉430079

出　　处：《中国食品添加剂》2024年第6期132-136,共5页China Food Additives

摘　　要：为了研究桑蚕蛋白复合粉的抗运动疲劳功效与作用机制,C57BL/6雄性小鼠分为对照组、低剂量组(50 mg/kg·d)、中剂量组(100 mg/kg·d)和高剂量组(200 mg/kg·d),灌胃30天后检测力竭游泳时间和运动疲劳标志性生化指标(血尿素氮、血乳酸、肌乳酸、肝糖原、肌糖原和骨骼肌中抗氧化相关酶活性)。与对照组相比,各剂量蚕蛋白复合粉组小鼠力竭游泳时间显著延长,血尿素氮、血乳酸、肌乳酸水平显著降低,肝糖原、肌糖原含量显著升高,骨骼肌中总抗氧化能力、谷胱甘肽过氧化物酶、超氧化物歧化酶和过氧化氢酶的活性显著升高,脂质过氧化产物丙二醛水平显著降低。桑蚕蛋白复合粉可以通过减少代谢废物乳酸与尿素氮的积累、增加肝糖原和肌糖原的储量、降低骨骼肌的氧化应激水平来发挥抗运动疲劳的功效。To study the anti-fatigue effects of silkworm protein complex powder and the underlying mechanisms,C57BL/6 male mice were divided into a control group,a low dose group(50 mg/kg·d),a medium dose group(100 mg/kg·d)and a high dose group(200 mg/kg·d).After 30 days of gavage,exhaustive swimming time and movement fatigue biochemical markers(blood urea nitrogen,blood lactic acid,muscular lactic acid,liver glycogen,muscle glycogen,and the activity of antioxidant-related enzymes in skeletal muscle)were tested.Compared with the control group,the exhaustive swimming time in the silkworm protein complex powder groups was significantly prolonged,the levels of blood urea nitrogen,muscular lactic acid and blood lactic acid were significantly decreased,the contents of liver glycogen and muscle glycogen were significantly increased,the total antioxidant capacity and the activity of glutathione peroxidase,superoxide dismutase,catalase in skeletal muscle were significantly elevated,and the level of malondialdehyde was significantly decreased.The silkworm protein complex powder exerted anti-exercise fatigue effects of mice by reducing the accumulation of lactic acid,muscular lactic acid and blood urea nitrogen,increasing the storage of liver glycogen and muscle glycogen,and alleviating the oxidative stress of skeletal muscle.

关 键 词：桑蚕蛋白复合粉 运动营养食品 抗运动疲劳 力竭游泳实验 

分 类 号：TS201[轻工技术与工程—食品科学]