4,4-二甲基甾醇生物活性研究进展  

Research progress on biological activity of 4,4-dimethylsterol

作　　者：谢亮亮[1] 李龙[1] 谢丹 郑立友 金俊[2] 金青哲[2] XIE Liangliang;LI Long;XIE Dan;ZHENG Liyou;JIN Jun;JIN Qingzhe(College of Biological and Food Engineering,Anhui Polytechnic University,Wuhu 241000,Anhui,China;School of Food Science and Technology,Jiangnan University,Wuxi 214122,Jiangsu,China)

机构地区：[1]安徽工程大学生物与食品工程学院,安徽芜湖241000 [2]江南大学食品学院,江苏无锡214122

出　　处：《中国油脂》2024年第7期47-53,共7页China Oils and Fats

基　　金：安徽省重点研究与开发计划(202104a06020030);安徽省自然科学基金(2308085MC111)。

摘　　要：旨在为4,4-二甲基甾醇在功能食品、保健品和药品等领域的开发应用提供科学的理论参考,概述了4,4-二甲基甾醇的来源、提取与分离纯化方法、鉴定方法及吸收与代谢,在此基础上对4,4-二甲基甾醇的降血糖、抗炎、减肥降脂、抑菌、抗肿瘤及抗阿尔茨海默病等方面表现的潜在生物活性进行了归纳总结,并对目前存在的问题提出相应的对策。4,4-二甲基甾醇是一种重要的植物甾醇,具有多种生物活性,表现出较大的潜在应用价值。In order to provide scientific theoretical reference for the application of 4,4-dimethylsterol in functional food,health products and drugs,the source,method of extraction,isolation and purification,identification method,and absorption and metabolism of 4,4-dimethylsterol were outlined,then the potential bioactivities of 4,4-dimethylsterol in terms of hypoglycemic,anti-inflammation,weight loss and lipid lowering,bacteriostasis,anti-tumor and anti-Alzheimer′s disease were summarized,and the corresponding countermeasures were proposed for the current problems.4,4-Dimethylsterol is a kind of important phytosterol with a variety of bioactivities and shows a large potential application value.

关 键 词：4 4-二甲基甾醇 糖尿病 肥胖 生物活性 

分 类 号：TS229[轻工技术与工程—粮食、油脂及植物蛋白工程] TQ645[轻工技术与工程—食品科学与工程]