NCPM模型用于非小细胞肺癌患者的效果评价  

Evaluation of the effectiveness of NCPM intervention for non-small cell lung cancer in patients

作　　者：李玉 黄哲思 邢乐幸 房宇坤 Li Yu;Huang Zhesi;Xing Lexing;Fang Yukun(Department of Respiratory Medicine,The 903 Hospital of the PLA Joint Logistics Support Force,Hangzhou 310013,Zhejiang Province,China)

机构地区：[1]解放军联勤保障部队第九〇三医院呼吸内科,杭州310013

出　　处：《中国基层医药》2024年第6期806-810,共5页Chinese Journal of Primary Medicine and Pharmacy

基　　金：浙江省教育厅一般科研项目(Y202352441)。

摘　　要：目的评价使用基于标准营养诊疗流程(NCPM)模型干预对非小细胞肺癌患者生存质量及营养状况的影响。方法选取解放军联勤保障部队第九〇三医院2023年1月至2024年2月治疗的非小细胞肺癌患者80例进行病例对照研究,按干预的方式不同分为对照组、研究组各40例。对照组使用传统的干预方式,研究组使用NCPM模型进行干预,比较两组干预前后的负性情绪、人体测量指标[上臂肌围(MAMC)、肱三头肌皮褶厚度(TSF)、身体质量指数(BMI)]、血液指标[血清总蛋白(TP)、血红蛋白(HB)、血清白蛋白(ALB)]、生活质量及免疫功能指标。结果干预后,研究组抑郁自评量表、焦虑自评量表评分分别为(17.37±1.78)分、(16.48±1.27)分,均明显低于对照组的(26.21±2.01)分、(25.11±1.36)分(t=20.82、29.33,均P<0.001);研究组BMI、TSF、MAMC分别为(19.62±0.18)kg/m^(2)、(9.85±0.23)mm、(25.81±0.40)cm,均明显高于对照组的(19.32±0.25)kg/m^(2)、(9.71±0.16)mm、(25.16±0.33)cm(t=6.16、3.16、20.12,均P<0.05);研究组HB、TP、ALB均明显高于对照组(t=3.93、4.41、6.15,均P<0.05);研究组的社会功能、物质生活、躯体功能、心理功能评分均明显高于对照组(t=8.64、3.44、3.62、7.71,均P<0.05);研究组CD4^(+)、CD4^(+)/CD8^(+)分别为(44.12±5.93)%、(1.94±0.43),均明显高于对照组的(40.08±5.21)%、(1.52±0.28),CD8^(+)为(23.18±2.11)%,低于对照组的(27.01±2.73)%,差异均有统计学意义(t=3.24、5.18、7.02,均P<0.05)。结论对于非小细胞肺癌患者使用基于NCPM模型下的干预方式能改善患者的饮食结构,规范营养管理流程,提高患者的生存质量。Objective To evaluate the effect of nutrition care process and model(NCPM)intervention on the quality of life and nutritional status in patients with non-small cell lung cancer.Methods A case-control study was conducted among 80 patients with non-small cell lung cancer treated at The 903 Hospital of the PLA Joint Logistics Support Force between January 2023 and February 2024.Based on different intervention methods,these patients were divided into a control group and a study group,with 40 patients in each group.The control group received traditional intervention,while the study group underwent intervention using the NCPM.Negative emotions,anthropometric indices(upper arm muscle circumference,triceps skin thickness,body mass index),blood indices(total serum protein,hemoglobin,serum albumin),quality of life,and immune function indices were compared between the two groups before and after the intervention.Results After the intervention,the scores on the Self-Rating Depression Scale and Self-Rating Anxiety Scale in the study group were(17.37±1.78)points and(16.48±1.27)points,respectively,which were significantly lower than those in the control group[(26.21±2.01)points,(25.11±1.36)points,t=20.82,29.33,both P<0.001].The body mass index,triceps skin thickness,and upper arm muscle circumference in the study group were(19.62±0.18)kg/m^(2),(9.85±0.23)mm,and(25.81±0.40)cm,respectively,which were significantly higher than those in the control group[(19.32±0.25)kg/m^(2),(9.71±0.16)mm,(25.16±0.33)cm,t=6.16,3.16,20.12,all P<0.05].The hemoglobin,total serum protein,and serum albumin levels in the study group were significantly higher compared with those in the control group(t=3.93,4.41,6.15,all P<0.05).The scores for social function,material life,physical function,and psychological function in the study group were significantly higher than those in the control group(t=8.64,3.44,3.62,7.71,all P<0.05).The study group had significantly higher CD4^(+)and CD4^(+)/CD8^(+)values,with(44.12±5.93)%and(1.94±0.43),respectively,c

关 键 词：癌 非小细胞肺 营养疗法 营养评价 模型 组织管理 生活质量 情绪 人体测量术 蛋白质类 

分 类 号：R734.2[医药卫生—肿瘤]