Evaluating the efficacy of percutaneous puncture biopsy guided by contrast-enhanced ultrasound for peripheral pulmonary lesions  

作　　者：Xiao Jiang Jun Chen Fang-Fang Gu Zhong-Rong Li Yu-Shan Song Jing-Jing Long Shu-Zhen Zhang Ting-Ting Xu Yong-Jun Tang Ji-Ying Gu Xiang-Ming Fang 

机构地区：[1]Department of Ultrasonography,Shidong Hospital,Yangpu District,Shidong Hospital Affiliated to University of Shanghai for Science and Technology,Shanghai 200438,China [2]Department of Ultrasonography,The Affiliated Wuxi People's Hospital of Nanjing Medical University,Wuxi People's Hospital,Wuxi Medical Center,Nanjing Medical University,Wuxi 214023,Jiangsu Province,China [3]Department of Radiology,The Affiliated Wuxi People's Hospital of Nanjing Medical University,Wuxi People's Hospital,Wuxi Medical Center,Nanjing Medical University,Wuxi 214023,Jiangsu Province,China

出　　处：《World Journal of Clinical Cases》2024年第19期3791-3799,共9页世界临床病例杂志

基　　金：the Ethic Committee of Wuxi People's Hospital(No.KY17071).

摘　　要：BACKGROUND The incidence and mortality of lung cancer have increased annually.Accurate diagnosis can help improve therapeutic efficacy of interventions and prognosis.Percutaneous lung biopsy is a reliable method for the clinical diagnosis of lung cancer.Ultrasound-guided percutaneous lung biopsy technology has been widely promoted and applied in recent years.AIM To investigate the diagnostic value of contrast-enhanced ultrasound(CEUS)-guided percutaneous biopsy in peripheral pulmonary lesions.METHODS We retrospectively collected data on 237 patients with peripheral thoracic focal lesions who underwent puncture biopsy at Wuxi People’s Hospital.The patients were randomly divided into two groups:The CEUS-guided before lesion puncture group(contrast group)and conventional ultrasound-guided group(control group).Analyze the diagnostic efficacy of the puncture biopsy,impact of tumor size,and number of puncture needles and complications were analyzed and compared between the two groups.RESULTS Accurate pathological results were obtained for 92.83%(220/237)of peripheral lung lesions during the first biopsy,with an accuracy rate of 95.8%(113/118)in the contrast group and 89.9%(107/119)in the control group.The difference in the area under the curve(AUC)between the contrast and the control groups was not statistically significant(0.952 vs 0.902,respectively;P>0.05).However,when the lesion diameter≥5 cm,the diagnostic AUC of the contrast group was higher than that of the control group(0.952 vs 0.902,respectively;P<0.05).In addition,the average number of puncture needles in the contrast group was lower than that in the control group(2.58±0.53 vs 2.90±0.56,respectively;P<0.05).CONCLUSION CEUS guidance can enhance the efficiency of puncture biopsy of peripheral pulmonary lesions,especially for lesions with a diameter≥5 cm.Therefore,CEUS guidance has high clinical diagnostic value in puncture biopsy of peripheral focal lung lesions.

关 键 词：Contrast-enhanced ultrasound Peripheral lung lesions Ultrasound guidance BIOPSY Peripheral thoracic focal lesions 

分 类 号：R734.2[医药卫生—肿瘤]