Cardiac implications in myasthenia gravis  

作　　者：Praveen Reddy Elmati Gowthami Sai Kogilathota Jagirdhar Salim Surani 

机构地区：[1]Department of Anesthesiology,Saint Clair Hospital,Dover,NJ 07801,United States [2]Department of Medicine,Saint Michaels Medical Center,Newark,NJ 07107,United States [3]Department of Medicine and Pharmacology,Texas A&M University,College Station,TX 77843,United States

出　　处：《World Journal of Clinical Cases》2024年第26期5863-5867,共5页世界临床病例杂志

摘　　要：This editorial aimed to consolidate the current evidence in literature on the association between myasthenia gravis(MG)and cardiac involvement,focusing on the impact of thymoma,antistriational antibodies,and late-onset MG.Additionally,the study aimed to explore the influence of genetic differences among populations on the association with cardiac disease.We conducted a review of existing literature in PubMed and Google Scholar to find relevant studies on cardiac involvement in MG.We created search criteria using a combination of free text words,including MG,antistriational antibodies,thymectomy,cardiomyopathy,myocarditis,arrhythmias,autonomic dysfunction.Relevant articles published in English language were analyzed and incorporated.The findings indicate a strong association between thymoma,myasthenic crisis,antistriational antibodies,and late-onset MG with cardiac involvement.The study also revealed that genetic differences among populations influence the risk of cardiac disease and electrocardiography(ECG)abnormalities in MG patients.Autonomic dysfunctions altered cardiac autonomic response and increased susceptibility to arrhythmias and sudden cardiac death in MG patients.The study supports the significance of thymoma,antistriational antibodies,and late-onset MG as key factors associated with cardiac involvement in MG patients.It emphasizes the importance of ECG as the initial test in managing MG patients,particularly in the perioperative period,to identify and genetic testing if needed to address their cardiac risk effectively.

关 键 词：Myasthenia gravis Antistriational antibodies THYMECTOMY CARDIOMYOPATHY MYOCARDITIS ARRHYTHMIAS Autonomic dysfunction 

分 类 号：R746.1[医药卫生—神经病学与精神病学]