Concurrent occurrence of adenocarcinoma and urothelial carcinoma of the prostate gland:A case report  

作　　者：Jhe Yuan Hsu Yi Sheng Lin Li Hua Huang Tang Yi Tsao Chao Yu Hsu Yen Chuan Ou Min Che Tung 

机构地区：[1]Division of Urology,Department of Surgery,Tungs'Taichung MetroHarbor Hospital,Taichung 435403,Taiwan [2]Department of Pathology,Tungs'Taichung MetroHarbor Hospital,Taichung 435403,Taiwan

出　　处：《World Journal of Clinical Cases》2024年第26期5952-5959,共8页世界临床病例杂志

摘　　要：BACKGROUND Adenocarcinoma is the most common subtype of prostate cancer.Prostatic urothelial carcinoma(UC)typically originates from the prostatic urethra.The concurrent occurrence of adenocarcinoma and UC of the prostate gland is uncommon.CASE SUMMARY We present the case of an 82-year-old male patient with simultaneous adenocarcinoma and UC of the prostate gland.The patient underwent a transrectal ultrasound-guided biopsy,and the pathology test revealed UC.Subsequently,transurethral laser prostatectomy was performed,and the pathology test indicated adenocarcinoma of the prostate with a Gleason score of 3+4 and highgrade UC.Therefore,the patient was treated with androgen deprivation therapy,systemic chemotherapy,and immunotherapy.Magnetic resonance imaging performed during follow-up revealed a prostate tumor classified as cT2cN1M0,stage IVA.Therefore,the patient underwent robotic-assisted radical prostatectomy and bilateral pelvic lymph node dissection.The final pathology test of the prostate gland revealed acinar-type adenocarcinoma,Gleason pattern 4+3,pT2N0M0,and high-grade UC.The patient regularly presented to the clinic for postoperative follow-up evaluations.He did not experience any urinary discomfort.CONCLUSION According to our literature review,this is the first reported case of coexisting adenocarcinoma and UC of the prostate gland.

关 键 词：ADENOCARCINOMA Urothelial carcinoma PROSTATE Coexist Case report 

分 类 号：R737.25[医药卫生—肿瘤]