结直肠上皮内瘤变及早期结直肠癌内镜治疗手术前后病理作用比照观察  

Comparison of colorectal intraepithelial neoplasia and pathological effects before and after endoscopic treatment for early colorectal cancer

作　　者：马瑄玉 丁雪峰 Ma Xuanyu;Ding Xuefeng(Affiliated Hospital of Gansu Medical College,Pingliang,Gansu 744000,China)

机构地区：[1]甘肃医学院附属医院,甘肃平凉744000

出　　处：《首都食品与医药》2024年第12期86-88,共3页Capital Food Medicine

基　　金：平凉市科技计划项目日(PL-STK-2022B-048)。

摘　　要：目的探讨结直肠上皮内瘤变以及早期结直肠癌患者实施内镜治疗手术前后呈现出的病理差异。方法对甘肃医学院附属医院时间范围处于2022年8月-2023年8月阶段的62例结直肠上皮内瘤变以及早期结直肠癌手术患者进行诊断研究;临床针对所有患者合理展开结直肠癌EMR/ESD(内镜下黏膜切除术/内镜黏膜下剥离术)治疗,对患者手术前后呈现出的病理差异展开分析。结果将横结肠病灶、降结肠病灶、升结肠病灶以及乙状结肠病灶术前活检结果以及术后病理结果呈现出的一致率展开比较,直肠病灶呈现出一定程度提升,但未呈现出明显差异(P>0.05)。结论对于结直肠癌患者而言,术前对其实施活检病理诊断后,同EMR/ESD术后病理比较,呈现出较低的符合率。但通过此种方式可对手术治疗方式的选择以及内镜随访提供一定程度依据。Objective To investigate the pathological differences of colorectal intraepithelial neoplasia and early colorectal cancer patients before and after endoscopic therapy.Methods A total of 62 patients with colorectal intraepithelial neoplasia and early colorectal cancer were diagnosed in our hospital from August 2022 to August 2023.Clinical EMR/ESD(endoscopic mucosal resection/endoscopic submucosal dissection)treatment for colorectal cancer was reasonably performed in all patients,and pathological differences before and after surgery were analyzed.Results Compared with the consistency rate of preoperative biopsy results and postoperative pathological results of transverse colon lesions,descending colon diseases,ascending colon diseases and sigmoid colon diseases,rectal lesions showed a certain degree of improvement,but no significant difference(P>0.05).Conclusion For patients with colorectal cancer,preoperative biopsy and pathological diagnosis have a lower coincidence rate compared with EMR/ESD postoperative pathology.However,this method can provide a certain degree of basis for the selection of surgical treatment and endoscopic follow-up.

关 键 词：早期结直肠癌内镜治疗 结直肠上皮内瘤变 手术 病理作用 一次性内窥镜用先端帽联合注水法 

分 类 号：R735[医药卫生—肿瘤]