数学模型在中药研究中的应用进展  

Application progress of mathematical models in Chinese medicine studies

作　　者：贺鹏 贺琪珺 李汪洋 谯茹 张伟龙 肖美凤[1,2,3] 潘雪 贺福元[1,2,3] HE Peng;HE Qijun;LI Wangyang;QIAO Ru;ZHANG Weilong;XIAO Meifeng;PAN Xue;HE Fuyuan(School of Pharmacy,Hunan University of Chinese Medicine,Changsha 410208,China;Hunan Provincial Key Laboratory of Drugability and Preparation Modification of Traditional Chinese Medicine,Changsha 410208,China;Supramolecular Mechanism and Mathematic-Physics Characterization for Chinese Materia Medica,Hunan University of Chinese Medicine,Changsha 410208,China;The First Hospital of Hunan University of Chinese Medicine,Changsha 410007,China;The Second Hospital of Hunan University of Chinese Medicine,Changsha 410005,China)

机构地区：[1]湖南中医药大学药学院,长沙410208 [2]中药成药性与制剂制备湖南省重点实验室,长沙410208 [3]湖南中医药大学中医药超分子机理与数理特征化实验室,长沙410208 [4]湖南中医药大学第一附属医院,长沙410007 [5]湖南中医药大学第二附属医院,长沙410005

出　　处：《中华中医药杂志》2024年第7期3575-3579,共5页China Journal of Traditional Chinese Medicine and Pharmacy

基　　金：国家自然科学基金项目(No.82274215);湖南省重点研发计划项目(No.2022SK2014);湖南省自然科学基金面上项目(No.2022JJ30453);湖南中医药大学2021年度校级科研基金项目(No.2021XJJJ002);湖南中医药大学研究生创新课题(No.2023CX140)。

摘　　要：数学模型在中医药研究应用中受到越来越多的关注。中医药学者在中医药思想和理论指导下,将数学引入中医药学研究中,将中医药学无边界的定性问题描绘转化为客观的数和形。数学模型将中医药学中模糊概率、非线性的量效关系等形象化和直观化阐述。通过建立数学模型重新构建标准的、规范的、全面的现代数字化中医药理论研究体系,对中药研究中的科学问题精确地定量分析,达到精确性、明确性、可预测性和可控制性的目的。文章概述数学模型在中药领域中的运用,分析总结数学模型在中药研究中的内容和意义,旨在为中医药研究者运用数学模型研究中医药理论提供参考。More and more attention has been paid to mathematical models in traditional Chinese medicine(TCM)research and application.Under the guidance of TCM thoughts and theories,researchers has introduced mathematical methods into the research of TCM,transforming the unbounded qualitative problem description of TCM into objective numbers and forms.The mathematical model visualizes the fuzzy probability and nonlinear quantity-effect relationship in TCM.Through the establishment of mathematical models,a set of standard,standardized and comprehensive modern digital theoretical research system of TCM is established,and scientific problems in TCM research are accurately and quantitatively analyzed to achieve the purpose of accuracy,clarity,predictability and controllability.This paper summarizes the application of mathematical models in the field of TCM,analyzes and summarizes the content and significance of mathematical models in the research of TCM,and aims to provide reference for the application of mathematical models in the research of TCM.

关 键 词：数学模型 数学应用 中医药 模型拟合 中药药性 

分 类 号：O29[理学—应用数学] R285.1[理学—数学]