Nanoscale Reorganization of Glutamate Receptors Underlies Synaptic Plasticity and Pathology  

作　　者：Jia-Hui Chen Ai-Hui Tang 

机构地区：[1]Hefei National Laboratory for Physical Sciences at the Microscale,CAS Key Laboratory of Brain Function and Disease,Neurodegenerative Disorder Research Center and Biomedical Sciences and Health Laboratory of Anhui Province,University of Science and Technology of China,Hefei,230027,China [2]Institute of Artificial Intelligence,Hefei Comprehensive National Science Center,Hefei,230088,China

出　　处：《Neuroscience Bulletin》2024年第6期840-844,共5页神经科学通报（英文版）

基　　金：supported by the STI2030-Major Project(2021ZD0202503);the Strategic Priority Research Program of the Chinese Academy of Sciences(XDB39010700);the China Postdoctoral Science Foundation(2021M703089);the Fundamental Research Funds from the University of Science and Technology of China(WK9110000141).

摘　　要：Excitatory synapses serve as the primary sites for information transmission between neurons in the brain.Seminal work over the past decades has identified and revealed multiple compositions and functions of the synaptic proteome in the postsynaptic density(PSD),including receptors,scaffold proteins,and signaling molecules,which work together to ensure stable and effective synaptic transmission.

关 键 词：RECEPTOR scale GLUTAMATE 

分 类 号：R338[医药卫生—人体生理学]