Unveiling the culprit:the fusobacterium lineage that populates colorectal cancer  

作　　者：Johannes Betge Matthias P.Ebert 

机构地区：[1]Department of Medicine Ⅱ,Medical Faculty Mannheim,Heidelberg University,Mannheim,Germany [2]Junior Clinical Cooperation Unit Translational Gastrointestinal Oncology and Preclinical Models,German Cancer Research Center(DKFZ),Heidelberg,Germany [3]DKFZ Hector Cancer Institute at University Medical Center,Mannheim,Germany [4]MMPU Microbiota Drug Metabolism and Cancer Therapy,European Molecular Biology Laboratory,Heidelberg,Germany

出　　处：《Signal Transduction and Targeted Therapy》2024年第6期2349-2350,共2页信号转导与靶向治疗（英文）

基　　金：supported by the Hector Ⅱ Foundation.

摘　　要：In a recent study published in Nature,Zepeda-Rivera et al.1 discovered that one distinct clade of Fusobacterium nucleatum animalis(Fna)dominates the colorectal cancer(CRC)tumor niche.The work unravels a more precise understanding of a major bacterial species associated with CRC progression,thereby establishing a new focus for future studies,which may aid to develop improved microbiome-based diagnostics and treatments(Fig.1).

关 键 词：COLORECTAL al. CANCER 

分 类 号：R735.34[医药卫生—肿瘤]