Jejunal sarcomatoid carcinoma:A case report and review of literature  

作　　者：Qian Feng Wei Yu Jing-Hui Feng Qiao Huang Gui-Xiang Xiao 

机构地区：[1]The First College of Clinical Medical Science,China Three Gorges University,Yichang 443000,Hubei Province,China [2]Department of Oncology,Yichang Central People's Hospital,Yichang 443000,Hubei Province,China [3]Institute of Pathology,Tongji Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430022,Hubei Province,China

出　　处：《World Journal of Gastrointestinal Oncology》2024年第8期3723-3731,共9页世界胃肠肿瘤学杂志（英文版）（电子版）

摘　　要：BACKGROUND Sarcomatoid carcinoma(SCA)of the jejunum is a rare and aggressive neoplasm affecting the smooth muscle cells of the jejunum.This study presents a recent case of jejunal SCA,detailing its diagnosis and treatment,thereby providing a reference for clinical practice.CASE SUMMARY A 65-year-old male presented to Yichang Central People's Hospital with a chief complaint of hemorrhoids.A computed tomography(CT)scan incidentally revealed multiple abnormal signals in the liver.Subsequent positron emission tomography/CT at Wuhan Union Hospital indicated malignant tumor progression,with a primary duodenal tumor and multiple metastases in the upper left abdomen.Intraoperatively,a large tumor was identified on the omentum.Histopathological and immunohistochemical analyses of the resected specimen confirmed the diagnosis of jejunal SCA.The patient received a combination therapy of sintilimab,nanoparticle albumin-bound paclitaxel,and anlotinib.Follow-up imaging demonstrated significant reduction of hepatic and peritoneal lesions.The patient has remained stable for over one year postoperatively.CONCLUSION This case suggests that chemotherapy,immunotherapy,plus targeted therapy may represent an optimal treatment for intestinal SCA,meriting further investigation.

关 键 词：Jejunal sarcomatoid carcinoma Targeted therapy IMMUNOTHERAPY CHEMOTHERAPY Case report 

分 类 号：R735.9[医药卫生—肿瘤]