Exploring the relationship between gut microbial ecology and inflammatory disease:An insight into health and immune function  

作　　者：Akashlina Marik Saheli Biswas Ena Ray Banerjee 

机构地区：[1]Department of Zoology,University of Calcutta,Kolkata 700019,West Bengal,India

出　　处：《World Journal of Immunology》2024年第1期1-16,共16页世界免疫学杂志

摘　　要：The immune system,host brain development,and general metabolism are all influenced by the gut bacteria.Bacteria make up the majority of the gut microbiota in mammals.The mouse has been the most often used animal model in preclinical biological research.In mice,Firmicutes and Clostridiales are prominent.On the other hand,Bacteroidaceae,Prevotellaceae,and Firmicutes are commonly found in humans.In this review,we performed a detailed study by focusing on a comparison between human and murine gut microbiomes,role of the microbiome and their secreted metabolites in regulating gut immunity to maintain homeostasis,and changes in the microbial composition in the dysbiotic state.

关 键 词：Gut microbiome IMMUNITY Inflammatory Bowel disease Diabetes DYSBIOSIS 

分 类 号：R392[医药卫生—免疫学] R37[医药卫生—基础医学]