藻油DHA微胶囊制备及稳态化递送技术研究进展  

Research Progress on Preparation and Steady Delivery Technology of Algae Oil DHA Microcapsule

作　　者：陈柏慧 田方 蔡路昀[2] Chen Baihui;Tian Fang;Cai Luyun(College of Food Science and Pharmacy,Key Laboratory of Health Risk Factors for Seafood of Zhejiang Province,Zhejiang Ocean University,Zhoushan 316022,Zhejiang;Ningbo Research Institute,College of Biosystems Engineering and Food Science,Zhejiang University,Ningbo 315100,Zhejiang)

机构地区：[1]浙江海洋大学食品科学与药学学院、浙江省海产品健康危害因素关键技术研究重点实验室,浙江舟山316022 [2]浙江大学宁波研究院生物系统工程与食品科学学院,浙江宁波315100

出　　处：《中国食品学报》2024年第7期414-424,共11页Journal of Chinese Institute Of Food Science and Technology

基　　金：浙江省基础公益研究计划项目(LGN22C200030);温州市重大科技创新攻关项目(ZN2021002)。

摘　　要：藻油DHA为多不饱和脂肪酸,具有促进大脑生长发育,预防心血管疾病,参与免疫调节等多种生理功能,然而其极不稳定,易受到光、热、水及CO_(2)等因素的影响,导致其氧化、变质。目前,国内外对藻油DHA稳态化递送技术的研究颇多,微胶囊技术是其中一种较为成熟的方法,且应用最为广泛,能够有效增强藻油DHA的递送能力、贮藏稳定性及生物利用度。本文概述藻油DHA的来源、理化性质、生物活性及其递送体系等,重点探讨藻油DHA微胶囊稳态化靶向递送技术,包括藻油DHA微胶囊的制备方法、递送体系、递送机制、影响因素等,旨在为拓宽藻油DHA在食品领域的应用范围,提供一定的理论依据。DHA(Docosahexaenoic acid),a polyunsaturated fatty acid,has many physiological functions,such as promoting brain growth and development,preventing cardiovascular diseases and participating in immune regulation.However,it is extremely unstable and easily affected by light,heat,water,CO2 and other factors,leading to its oxidation and deterioration.There are many studies on the steady delivery technology of algae oil DHA at home and abroad.Microcapsule technology is one of the more mature methods.It is widely used and can effectively enhance the delivery capacity,storage stability,and bioavailability of algae oil DHA.In this paper,the source,physical and chemical properties,biological activity and delivery system of algae oil DHA were summarized,and the steady-state targeted delivery technology of algae oil DHA microcapsules was emphatically discussed,including the preparation method,delivery system,delivery mechanism and influencing factors of algae oil DHA microcapsules,to provide some theoretical basis and reference for broadening the application range of algae oil DHA in food field.

关 键 词：藻油DHA 微胶囊 喷雾干燥法 稳态化 递送体系 

分 类 号：TS225.1[轻工技术与工程—粮食、油脂及植物蛋白工程]