胆道微生物群在常见胆道疾病发生发展中的作用  

Role of biliary microbiota in the development and progression of common biliary tract diseases

作　　者：霍丽 畅智慧[1] HUO Li;CHANG Zhihui(Department of Radiology,Shengjing Hospital of China Medical University,Shenyang 110004,China)

机构地区：[1]中国医科大学附属盛京医院放射科,沈阳110004

出　　处：《临床肝胆病杂志》2024年第8期1699-1703,共5页Journal of Clinical Hepatology

基　　金：国家自然科学基金(82272097)。

摘　　要：胆道微生物群的组成与胆道疾病的发生和发展密切相关。胆道微生物群的失衡可能导致胆结石、胆道感染、自身免疫性胆管炎和胆管癌等一系列胆道疾病的发生。本文整理了胆道微生物群与胆道疾病关系的相关文献并进行综述,总结胆道微生物群对各种胆道疾病的影响,以及胆道中特定菌群在胆道疾病中发挥的作用,以期指导进一步的临床研究,为胆道疾病的预防、诊断、治疗提供新见解。The composition of biliary microbiota is closely associated with the development and progression of biliary diseases,and imbalance of biliary microbiota may lead to a series of biliary tract diseases such as gallstones,biliary tract infections,autoimmune cholangitis,and cholangiocarcinoma.This article reviews the articles on the association between biliary microbiota and biliary tract diseases and summarizes the influence of biliary microbiota on various biliary tract diseases and the role of specific bacterial flora in biliary tract diseases,in order to guide further clinical research and provide new ideas for the prevention,diagnosis,and treatment of biliary tract diseases.

关 键 词：胆石 胆管炎 胆道感染 胆管上皮癌 微生物群 

分 类 号：R575.7[医药卫生—消化系统]