蓝莓花色苷抗疲劳功效及机制研究  

Anti-Fatigue Effect and Mechanism of Blueberry Anthocyanins

作　　者：张晓俭 范丽霞[1] ZHANG Xiaojian;FAN Lixia(Henan Industry and Trade Vocational College,Zhengzhou 451191,China)

机构地区：[1]河南工业贸易职业学院,河南郑州451191

出　　处：《食品科技》2024年第7期231-236,共6页Food Science and Technology

摘　　要：目的:探究蓝莓花色苷对小鼠运动疲劳的影响。方法:采用灌胃方式喂食不同剂量蓝莓花色苷,以蒸馏水作为阴性对照,牛磺酸作为阳性对照,通过力竭跑步试验评价抗疲劳活性,同时测定疲劳相关指标。结果:提取蓝莓花色苷质量浓度为(432.15±9.71)mg/g,和阴性对照组相比,不同剂量组和牛磺酸组对小鼠体质量和器官指数无显著影响(P>0.05);高剂量组蓝莓花色苷显著延长了小鼠力竭跑步时间(P<0.05),肌酸激酶(Creatine kinase, CK)、血清乳酸(Blood lactic acid, BLA)、血清尿素氮(Blook urea nitrogen, BUN)和丙二醛(Malondialdehyde, MDA)水平最低(P<0.05),肝糖原、肌糖原、乳酸脱氢酶(Lactate dehydrogenase, LDH)、超氧化物歧化酶(Superoxide dismutase,SOD)、过氧化氢酶(Catalase,CAT)和谷胱甘肽过氧化物酶(Glutathione peroxidase, GSH-Px)水平最高(P<0.05),与牛磺酸组效果相当。结论:研究表明蓝莓花色苷能改善小鼠运动疲劳,可为功能性食品的开发提供原料。Objective:To explore the effect of blueberry anthocyanins on exercise fatigue in mice.Methods:Different doses of blueberry anthocyanins were fed by gavage,distilled water was used as negative control and taurine was used as positive control.The anti-fatigue activity was evaluated by exhaustion running test,and fatigue related indexes were determined.Results:The concentration of blueberry anthocyanins was(432.15±9.71)mg/g.Compared with the negative control group,different dosage groups and taurine group had no significant effects on body weight and organ index of mice(P<0.05).High-dose blueberry anthocyanins significantly extended the exhausted running time of mice(P<0.05),creatine kinase(CK),blood lactic acid(BLA),blook urea nitrogen(BUN)and malondialdehyde(MDA)levels were the lowest(P<0.05),liver glycogen,muscle glycogen,lactate dehydrogenase(LDH),superoxide dismutase(SOD),catalase(CAT)and glutathione peroxidase(GSH-Px)levels were the highest(P<0.05),the effect was similar to that of taurine group.Conclusion:The results suggest that blueberry anthocyanins could improve the exercise fatigue of mice and provide raw materials for the development of functional food.

关 键 词：蓝莓 花色苷 抗疲劳 力竭跑步 

分 类 号：TS201.2[轻工技术与工程—食品科学]