沙棘活性成分以及抗肿瘤和抗衰老活性  

Bioactive components of Hippophae rhamnoides Linnaeus and their anti-cancer and anti-aging activities

作　　者：朱浩铭 芦琳琳 郭丽君 张士璀 ZHU Haoming;LU Linlin;GUO Lijun;ZHANG Shicui(College of Life and Geographic Sciences,Key Laboratory of Biological Resources and Ecology of Pamirs Plateau in Xinjiang Uygur Autonomous Region,Kashi University,Xinjiang 844000;Qingdao Cancer Prevention and Treatment Research Institute,Qingdao Central Hospital,University of Health and Rehabilitation Sciences;Institute of Evolution&Marine Biodiversity,Ocean University of China)

机构地区：[1]喀什大学生命与地理科学学院,新疆帕米尔高原生物资源与生态重点实验室,新疆844000 [2]康复大学青岛中心医院,肿瘤预防治疗研究院 [3]中国海洋大学海洋生物多样性与进化研究所

出　　处：《南通大学学报（医学版）》2024年第4期367-374,共8页Journal of Nantong University(Medical sciences)

基　　金：国家自然科学基金资助项目(32270434);喀什大学科研启动基金资助项目(022023184);企业委托项目(02202350)。

摘　　要：随着生活方式的改变和人口老龄化,老年相关疾病如癌症和阿尔茨海默病等神经退行性疾病对人类健康构成严重威胁。从植物中获取天然的抗癌和抗衰老活性成分,成为倍受国内外学者重视的一个热点。沙棘含有丰富的生物活性成分,包括酚类化合物、酮类化合物、维生素、不饱和脂肪酸和氨基酸,已被证实具有良好的抗癌和抗衰老活性。本文对沙棘活性成分以及在抗肿瘤和抗衰老方面的最新研究进展作简要概述。With changes in lifestyle and occurrence of aging population,age-related diseases such as cancer and Alzheimer's disease neurodegenerative diseases,pose an increasingly serious threat to human health.Searching for natural anti-cancer and anti-aging bioactive products from plants is becoming a hot topic which is highly valued by scientists home and abroad.Hippophae rhamnoides Linnaeus contains rich bioactive components including polyphenols,flavonoids,vitamins,unsaturated fat acids and amino acids,and has been shown by many studies to possess promising anti-cancer and anti-aging properties.This review briefly summarizes the current progress on the bioactive components of Hippophae rhamnoides Linnaeus and their anti-cancer and anti-aging activities.

关 键 词：沙棘 生物活性成分 抗癌活性 抗衰老活性 

分 类 号：R284.2[医药卫生—中药学]