Ethical concerns in aging research:perspectives of global frontline researchers  

作　　者：Yaojin Peng Lulu Ding Zhenyu Xiao Moshi Song Jianwei Lv Guang-Hui Liu 

机构地区：[1]Key Laboratory of Organ Regeneration and Reconstruction,State Key Laboratory of Stem Cell and Reproductive Biology,Institute of Zoology,Chinese Academy of Sciences,Beijing 100101,China [2]University of Chinese Academy of Sciences,Beijing 100049,China [3]Beijing Institute for Stem Cell and Regenerative Medicine,Beijing 100101,China [4]Institute for Stem Cell and Regeneration,Chinese Academy of Sciences,Beijing 100101,China [5]Aging Biomarker Consortium(ABC),Beijing 100101,China [6]School of Life Science,Beijing Institute of Technology,Beijing 100081,China [7]School of Life Sciences,Xiamen University,Xiamen 361102,China [8]Advanced Innovation Center for Human Brain Protection and National Clinical Research Center for Geriatric Disorders,Xuanwu Hospital,Capital Medical University,Beijing 100053,China [9]Aging Translational Medicine Center,International Center for Aging and Cancer,Beijing Municipal Geriatric Medical Research Center,Xuanwu Hospital,Capital Medical University,Beijing 100053,China

出　　处：《Science China(Life Sciences)》2024年第10期2149-2156,共8页中国科学（生命科学英文版）

基　　金：supported by the National Key Research and Development Program of China(2022YFA1104701);the Youth Innovation Promotion Association of the Chinese Academy of Sciences(2021080);the CAS Project for Young Scientists in Basic Research(YSBR-076);the National Natural Science Foundation of China(81921006,92149301,92368112)。

摘　　要：This study investigated the ethical landscape of aging research amid the increasing global focus on extending the human lifespan and health span.Our global survey of 180 researchers across 38 jurisdictions revealed divergent perceptions of aging,a consensus regarding the feasibility of delaying aging,and multiple perspectives regarding lifespan extension.The present findings underscore a paradigm shift toward inclusive and ethically sound research,emphasizing the need for an approach that strikes a balance between basic and clinical research.In addition,this study highlighted key ethical concerns in aging research,including the effects of misleading advertising,potential inequality in access to aging interventions,and risks pertaining to the extrapolation of research findings from lower-model organisms to humans.The insights presented in this paper call for an integrated approach for overcoming the complex ethical and societal challenges in aging research to ensure responsible and equitable advancements in this burgeoning field.

关 键 词：AGING ethical landscape ETHICS surveys and questionnaires 

分 类 号：B82-05[哲学宗教—伦理学] C924.1[社会学—人口学] C913.6