Cellular models of stress resistance may pave ways to fight neurodegenerative diseases  

作　　者：Thu Nguyen Minh Pham Christian Behl 

机构地区：[1]Institute of Pathobiochemistry,University Medical Center of the Johannes Gutenberg University,Mainz,Germany

出　　处：《Neural Regeneration Research》2025年第9期2579-2580,共2页中国神经再生研究（英文版）

基　　金：supported by a grant of the Deutsche Forschungsgemeinschaft(DFG;CRC1177 and joint DFG/ANR grant)(to CB);a fellowship of the Deutscher Akademischer Austauschdienst(DAAD)(to TNMP)。

摘　　要：Alzheimer's disease(AD),the most common form of neurodegeneration,is characterized by selective neuronal vulnerability and brain regionselective neuron demise.The entorhinal cortex and hippoc,ampal CA1 projection neurons are at greater risk in AD whereas other regions display resistance to neurodegeneration.Interestingly,the cerebellum,a phylogenetically very old region,is affected only very late in the disease progression.

关 键 词：CORTEX resistance ALZHEIMER 

分 类 号：R741[医药卫生—神经病学与精神病学]