Acute severe hypokalemia caused by treatment of tongue squamous cell carcinoma with docetaxel and cisplatin:A case report  

作　　者：Hong-Mei Jiang Rong Sun Bing-Jie Ning Xue-Qin Yang Xiao-Ju Zhu 

机构地区：[1]Department of Cancer Center,Daping Hospital,Army Medical University,Chongqing 400042,China

出　　处：《World Journal of Clinical Oncology》2024年第10期1309-1314,共6页世界临床肿瘤学杂志（英文）

基　　金：Supported by the Chongqing medical scientific research project(a joint project of the Chongqing Health Commission and Science and Technology),No.2020ZY023716.

摘　　要：BACKGROUND The tongue squamous cell carcinoma(TSCC)is an oral malignant tumor arising from the squamous epithelium of the tongue mucosa,characterized by a high malignant degree,invasive growth,early lymph node metastasis,and poor prognosis.Paclitaxel,represented by docetaxel,is now the standard first-line treatment for head and neck squamous cell carcinoma.Docetaxel,which belongs to the class of drugs known as paclitaxel,is an antitumor drug that inhibits cell mitosis and proliferation.Its adverse effects include myelosuppression,hair loss,gastrointestinal reactions,fluid retention,and allergic reactions.However,hypokalemia is rare,most cases are mild or moderate,and severe hypokalemia is seldom reported.symptoms of adverse effects early.It is necessary to be considerate regarding individual differences between patients when selecting chemotherapy regimens and adhere to the principle of individualized treatment.Following multiple cycles of chemotherapy,patients should be aware of the accumulation of toxic side effects and receive blood tests reviewed within 24 hours of completion.It is essential to monitor electrolyte levels in patients suffering from severe gastrointestinal reactions to avoid complications that may result in death.

关 键 词：Tongue squamous cell carcinoma DOCETAXEL HYPOKALEMIA HYPOMAGNESEMIA Case report 

分 类 号：R739.8[医药卫生—肿瘤]