Evolving of treatment options for cerebral infarction  

作　　者：Qiong-Yue Cao Zheng Li 

机构地区：[1]School of Life Sciences,Jiangsu Normal University,Xuzhou 221116,Jiangsu Province,China [2]Jiangsu Engineering Research Center of Cardiovascular Drugs Targeting Endothelial Cells,College of Health Sciences,School of Life Sciences,Jiangsu Normal University,Xuzhou 221116,Jiangsu Province,China

出　　处：《World Journal of Clinical Cases》2024年第32期6534-6537,共4页世界临床病例杂志（英文）

摘　　要：In this editorial,we comment on a recent article which addressed the therapeutic effect of aspirin plus edaravone in patients with cerebral infarction(CI).Herein,we outline the progress in therapy of CI.Apart from thrombolysis,aspirin is the most effective treatment for CI.Edaravone,a free radical scavenger,reduces endothelial cell damage and delays neuronal cell death.Aspirin plus edaravone mitigates damage to brain tissue by different mechanisms,thereby expediting the reinstation of neurological function.However,the nephrotoxic effect of edaravone,along with gastrointestinal bleeding associated with aspirin,may restrict this combination therapy.Although clinical studies have demonstrated the efficacy of thrombolytic therapy and mechanical thrombectomy,patients receiving these treatments experience modest efficacy and many adverse events.Moreover,interest in exploring natural medicines for CI is increasing,and they appear to have a high potential to protect against CI.The evolution of therapeutic strategies is expected to improve clinical outcomes of patients with CI.

关 键 词：Cerebral infarction Treatment Thrombolytic therapy ASPIRIN EDARAVONE Natural medicine 

分 类 号：R743.3[医药卫生—神经病学与精神病学]