EDARAVONE

作品数：77被引量：334H指数：8
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相关领域：医药卫生更多>>
相关作者：高俊玲赵雅宁田艳霞崔建忠张文丽更多>>
相关机构：华北煤炭医学院华中科技大学唐山工人医院华北理工大学更多>>
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相关基金：国家自然科学基金河北省博士后基金天津市自然科学基金山东省自然科学基金更多>>
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The Study on the Effect of Huoxue Tongmai Capsules Combined with Edaravone Right Camphor on Serum Inflammatory Factors and Its Clinical Efficacy in Patients with Acute Cerebral Infarction
《Journal of Biosciences and Medicines》2025年第2期148-157,共10页Yaojie Cai Yan Chen Yuping He 
Objective: To explore the therapeutic effect of Huoxue Tongmai capsule combined with edaravone right camphor on patients with acute cerebral infarction (Acute Cerebral Infarction) and the effect of combination therapy...
关键词：Acute Cerebral Infarction Huoxue Tongmai Capsule Edaravone Right Camphor Inflammatory Factors Nerve Function 
Rationale and design of Treatment of Acute Ischaemic Stroke with Edaravone Dexborneol Ⅱ(TASTE-2):a multicentre randomised controlled trial被引量：1
《Stroke & Vascular Neurology》2024年第6期730-737,共8页Chunjuan Wang Hong-Qiu Gu Qiang Dong Anding Xu Ning Wang Yi Yang Feng Wang Yongjun Wang 
Simcere Pharmaceutical Group,the Ministry of Science and Technology of the People’s Republic of China(2022YFC2504902,2022YFC2504904);National Natural Science Foundation of China(81801152,92046016);CAMS Innovation Fund for Medical Sciences(2019-I2M 5-029);Beijing Municipal Committee of Science and Technology(Z201100005620010,Z211100002921064).
Background Edaravone dexborneol is believed to be a novel cytoprotective drug,demonstrating a synergistic combination of antioxidative and anti-inflammatory properties in animal models.The Treatment of Acute Ischaemic...
关键词：protective CENTRE RANDOM 
Evolving of treatment options for cerebral infarction
《World Journal of Clinical Cases》2024年第32期6534-6537,共4页Qiong-Yue Cao Zheng Li 
In this editorial,we comment on a recent article which addressed the therapeutic effect of aspirin plus edaravone in patients with cerebral infarction(CI).Herein,we outline the progress in therapy of CI.Apart from thr...
关键词：Cerebral infarction Treatment Thrombolytic therapy ASPIRIN EDARAVONE Natural medicine 
“Three-in-one” strategy of trifluoromethyl regulated blood-brain barrier permeable fluorescent probe for peroxynitrite and antiepileptic evaluation of edaravone
《Chinese Chemical Letters》2024年第10期360-363,共4页Lei Shen Hongmei Liu Ming Jin Jinchao Zhang Caixia Yin Shuxiang Wang Yutao Yang 
supported by the National Natural Science Foundation of China(Nos.22177025,21807021,22325703,22177026);Science Fund for Creative Research Groups of Nature Science Foundation of Hebei Province(No.B2021201038);the Interdisciplinary Research Program of Natural Science of Hebei University(No.DXK202113);the Central Government Guided Local Science,Technology Development Fund(Hebei Province,No.216Z2603G);National High-End Foreign Expert Recruitment Plan(No.G2022003007L)。
Epilepsy,as a chronic neurological disease of the brain,is closely related to oxidative stress,and the peroxynitrite(ONOO-)significantly rise up in this event.Therefore,ONOO-is considered as a potential biomarker for ...
关键词：Fluorescent probe Blood-brain barrier PEROXYNITRITE EPILEPSY Drug repurposing 
Therapeutic effect and psychological impact of aspirin plus edaravone on patients with cerebral infarction
《World Journal of Psychiatry》2024年第5期644-652,共9页Tian-Shu Wang Li-Jun Jing 
BACKGROUND Cerebral infarction(CI)is characterized by a high prevalence,disability,and mortality.Timely or improper treatment greatly affects patient prognosis.AIM To explore the drug efficacy of aspirin plus edaravon...
关键词：ASPIRIN EDARAVONE Cerebral infarction EFFICACY Quality of life 
Edaravone-loaded poly(amino acid) nanogel inhibits ferroptosis for neuroprotection in cerebral ischemia injury被引量：1
《Asian Journal of Pharmaceutical Sciences》2024年第2期89-101,共13页Yunhan Zhang Zhulin Zou Shuang Liu Fangfang Chen Minglu Li Haoyang Zou Haiyan Liu Jianxun Ding 
supported by the National Natural Science Foundation of China(Grant No.U23A20591,52203201,52173149,and 81971174);the Youth Talents Promotion Project of Jilin Province(Grant No.202019);the Science and Technology Development Program of Jilin Province(Grant No.20210101114JC);Research Cooperation Platform Project of Sino-Japanese Friendship Hospital of Jilin University and Basic Medical School of Jilin University(Grant No.KYXZ2022JC04).
Neurological injury caused by ischemic stroke is a major cause of permanent disability and death. The currently available neuroprotective drugs fail to achieve desired therapeutic efficacy mainly due to short circulat...
关键词：Poly(amino acid)nanogel Controlled drug delivery Inhibition of ferroptosis NEUROPROTECTION Cerebral ischenia injury therapy 
Edaravone administration and its potential association with a new clinical syndrome in cerebral infarction patients:Three case reports
《World Journal of Clinical Cases》2023年第19期4648-4654,共7页Liu Yang Xin Xu Liang Wang Ke-Bin Zeng Xue-Feng Wang 
BACKGROUND Edaravone is a widely used treatment for patients with cerebral infarction and,in most cases,edaravone-induced side effects are mild.However,edaravone-related adverse reactions have been receiving increasin...
关键词：EDARAVONE Sudden death PATIENTS Cerebral infarction Case report 
Safety of butylphthalide and edaravone in patients with ischemic stroke:a multicenter real-world study被引量：3
《Journal of Geriatric Cardiology》2023年第4期293-308,共16页Shu-Xian LYU Dong-Fang QIAN Yu-Fei FENG Cheng-Wu SHEN Lu-Bo GUO Jian-Tao LYU Peng-Fei JIN Ting LI Si-Yuan TAN Zi-Xuan ZHANG Lin HUANG Xue ZHONG Le-Qun SU Xin HU Xin HUANG Xue-Yan CUI 
supported by the China Society for Drug Regulation(CSDR)Project:exploration of criteria for post-marketing risk assessment of medications using real-world data(DRM2021008);the Special Clinical Pharmacy Program of Shandong Medical Association(YXH2022ZX004)。
BACKGROUND Butylphthalide(NBP)and edaravone(EDV)injection are common acute ischemic stroke medications in China,but there is a lack of large real-world safety studies on them.This study aimed to determine the incidenc...
关键词：PATIENTS DRUGS injection 
Use of edaravone to decrease perioperative neurocognitive disorders in elderly patients with hip replacement被引量：1
《Chinese Medical Journal》2023年第5期629-630,共2页Yujing Yuan Liujiazi Shao Xin Luo Fushan Xue 
To the Editor:By a randomized controlled trial,Xi et at[1]assessed the effects of edaravone on the development of postoperative delirium(POD)and perioperative neurocognitive disorders(PND)in elderly patients with hip ...
关键词：patients SURGERY DISORDERS 
The Protective Effects of Preventive Atomisation Inhalation of Edaravone on the Lung Tissues of Rats with Smoke Inhalation Injury
《American Journal of Molecular Biology》2022年第4期147-157,共11页Ruluo Qian Changshuan Xiao Yaping Liu Jingzhe Yang 
Objective: To investigate the protective effects of the atomisation inhalation of edaravone on the lung tissues of rats with smoke inhalation injury. Methods: Forty male Sprague-Dawley (SD) rats were randomly divided ...
关键词：EDARAVONE RATS PREVENTION Smoke Inhalation Injury 
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