Interoception mediates the association between social support and sociability in patients with major depressive disorder  

作　　者：Wen-Liang Wang Ji-Kang Liu Yi-Fan Sun Xiao-Hong Liu Yu-Hang Ma Xue-Zheng Gao Li-Min Chen Zhen-He Zhou Hong-Liang Zhou 

机构地区：[1]Department of Psychiatry,The Affiliated Mental Health Center of Jiangnan University,Wuxi 214151,Jiangsu Province,China [2]Department of Psychiatry,The Affiliated Mental Health Center of Nanjing Medical University,Wuxi 214151,Jiangsu Province,China [3]Department of Psychology,The Affiliated Hospital of Jiangnan University,Wuxi 214151,Jiangsu Province,China

出　　处：《World Journal of Psychiatry》2024年第10期1484-1494,共11页世界精神病学杂志（英文）

基　　金：Supported by the Wuxi Municipal Health Commission Major Project,No.202107.

摘　　要：BACKGROUND Interoception dysfunction has an important impact on the onset and development of major depressive disorder(MDD).Social support serves as a protective factor against MDD,and sociability also plays a significant role in this condition.These interconnected constructs-social support and sociability-play pivotal roles in MDD.However,no research on the mechanisms underlying the associations be-tween social support and sociability,particularly the potential role of interocep-tion,have been reported.ception,social support,and sociability,respectively.A mediation analysis model for the eight dimensions of intero-ception(noticing,not distracting,not worrying,attention regulation,emotional awareness,self-regulation,body listening,and trust),social support,and sociability were established to evaluate the mediating effects.RESULTS A partial correlation analysis of eight dimensions of the MAIA-2,SSRS,and TSBI scores,with demographic data as control variables,revealed pairwise correlations between the SSRS score and both the MAIA-2 score and TSBI score.In the major depression(MD)group,the SSRS score had a positive direct effect on the TSBI score,while the scores for body listening,emotional awareness,self-regulation,and trust in the MAIA-2C had indirect effects on the TSBI score.In the HC group,the SSRS score had a positive direct effect on the TSBI score,and the scores for attention regulation,emotional awareness,self-regulation,and trust in the MAIA-2C had indirect effects on the TSBI score.The proportion of mediators in the MD group was lower than that in the HC group.CONCLUSION Interoceptive awareness is a mediating factor in the association between social support and sociability in both HCs and depressed patients.Training in interoceptive awareness might not only help improve emotional regulation in depressed patients but also enhance their social skills and support networks.

关 键 词：INTEROCEPTION Social support SOCIABILITY Major depression Mediation analysis 

分 类 号：R749.4[医药卫生—神经病学与精神病学]