National Natural Science Foundation of China(82230071,82172098);Integrated Project of Major Research Plan of National Natural Science Foundation of China(92249303);Shanghai Committee of Science and Technology(23141900600,Laboratory Animal Research Project);Shanghai Clinical Research Plan of SHDC2023CRT01;Young Elite Scientist Sponsorship Program by China Association for Science and Technology(YESS20230049)。
Accumulating research has shed light on the significance of skeletal interoception,in maintaining physiological and metabolic homeostasis related to bone health.This review provides a comprehensive analysis of how ske...
supported by grants from the National Natural Science Foundation of China(32371060 and 32271065);the Lingang Laboratory(LG-QS-202203-06 and LG-QS-202203-02);the Chinese Academy of Sciences,and Benyuan Charity Foundation.
The insula is a complex brain region central to the orchestration of taste perception,interoception,emotion,and decision-making.Recent research has shed light on the intricate connections between the insula and other ...
Supported by the Wuxi Municipal Health Commission Major Project,No.202107.
BACKGROUND Interoception dysfunction has an important impact on the onset and development of major depressive disorder(MDD).Social support serves as a protective factor against MDD,and sociability also plays a signifi...
supported by the National Natural Science Foundation of China(82072432).
The interoception maintains proper physiological conditions and metabolic homeostasis by releasing regulatory signals after perceving changes in the internal state of the organism.Among its various forms,skeletal inte...
This research was supported by NIH National Institute on Aging under Award Number R01 AG076783,R01 AG068997 and P01 AG066603(to X.C.).
Bone is a mechanosensitive tissue and undergoes constant remodeling to adapt to the mechanical loading environment.However,it is unclear whether the signals of bone cells in response to mechanical stress are processed...
Little is known about the relationship between bone and brain;however,accumulated clinical and experimental evidence suggests that there is crosstalk and a bilateral dependence between the two organs.1 A recent review...
supported by National Institute on Aging of the National Institutes of Health under Award Number R01 AG068997 and P01 AG066603(to X.C.).
Skeletal interoception regulates bone homeostasis through the prostaglandin E2(PGE2)concentration in bone.Vertebral endplates undergo ossification and become highly porous during intervertebral disc degeneration and a...