Trends in Mortality of Cirrhosis in China: An Analysis of the China Death Surveillance Database from 2008 to 2020  

作　　者：Xiaoxiao Wang Huixin Liu Jinlei Qi Lijun Wang Peng Yin Feng Liu Lai Wei Yu Wang Maigeng Zhou Huiying Rao 

机构地区：[1]Peking University People’s Hospital,Peking University Hepatology Institute,Beijing Key Laboratory of Hepatitis C and Immunotherapy for Liver Diseases,Beijing International Cooperation Base for Science and Technology on NAFLD Diagnosis,Beijing,China [2]Department of Clinical Epidemiology and Biostatistics,Peking University People’s Hospital,Beijing,China [3]National Center for Chronic Noncommunicable Disease Control and Prevention,Chinese Center for Disease Control and Prevention,Beijing,China [4]Beijing Tsinghua Changgung Hospital,Tsinghua University,Beijing,China [5]Chinese Foundation for Hepatitis Prevention and Control,Beijing,China

出　　处：《Journal of Clinical and Translational Hepatology》2024年第3期236-244,共9页临床与转化肝病杂志（英文版）

基　　金：supported by the National Natural Science Foundation of China(NSFC)(82300660 XW,81870406 HR and 81602939 HL);Beijing Natural Science Foundation(7232195 XW);Peking University Medicine Sailing Program for Young Scholars’Scientific&Technological Innovation(BMU2023YFJHPY025);Capital’s Funds for Health Improvement and Research(2020-4-4087 HL);Peking University People’s Hospital Scientific Research Development Funds(RDJP2022-60 XW)and Qi-Min Project.

摘　　要：Background and Aims:China accounts for 14.9%of total cirrhosis deaths worldwide.A detailed and comprehensive understanding of the contemporary status of cirrhosis mortality in China is crucial for establishing strategies for intervention and decreasing the disease burden of cirrhosis worldwide.The study aimed to report the cirrhosis mortality rates in our whole country or province over time.Methods:Mortality data from 2008 to 2020 were retrieved from the Disease Surveillance Point System(DSPs)of the Chinese Center for Disease Control and Prevention.The crude mortality rate and age-standardized mortality rate of patients with cirrhosis were stratified by sex,residential location,and region.The average annual percentage change(AAPC)in cirrhosis mortality rates from 2008 to 2020 was also calculated.Results:The crude mortality rate of cirrhosis was 4.57/100,000 people in 2020.Compared with females and individuals living in urban areas,males and people living in rural areas had greater age-standardized mortality.The crude mortality rate and age-standardized mortality rate in provinces in Southwest China(Guangxi,Yunnan,Guizhou,and Qinghai)were greater than those in other provinces.Moreover,with increasing age,the age-specific mortality rate increased significantly.From 2008 to 2020,the mortality rate of cirrhosis in China decreased except for in males aged 50–59 years,females aged 45–49 years and females aged 80–84 years.Conclusions:The mortality rate of patients with cirrhosis in China decreased from 2008 to 2020.In the future,interventions of cirrhosis mortality control need to pay more attention to all males,females aged 45–49 and 80–84 years,and people living in rural areas and in provinces in Southwest China.

关 键 词：CIRRHOSIS MORTALITY TREND China 

分 类 号：R575.2[医药卫生—消化系统]