Exercise and nutrition benefit skeletal muscle:From influence factor and intervention strategy to molecular mechanism  

作　　者：Lili Feng Bowen Li Su Sean Yong Xiaonan Wu Zhenjun Tian 

机构地区：[1]College of Education,Physical Education Department,Zhejiang University,Hangzhou,310058,China [2]The Information and Communication College,National University of Defense Technology,Xi'an,710106,China [3]Institute of Sports Biology,College of Physical Education,Shaanxi Normal University,Xi'an,710119,China

出　　处：《Sports Medicine and Health Science》2024年第4期302-314,共13页运动医学与健康科学（英文）

基　　金：funded by National Natural Science Foundation of China,grant number“32171128”.

摘　　要：Sarcopenia is a progressive systemic skeletal muscle disease induced by various physiological and pathological factors,including aging,malnutrition,denervation,and cardiovascular diseases,manifesting as the decline of skeletal muscle mass and function.Both exercise and nutrition produce beneficial effects on skeletal muscle growth and are viewed as feasible strategies to prevent sarcopenia.Mechanisms involve regulating blood flow,oxidative stress,inflammation,apoptosis,protein synthesis and degradation,and satellite cell activation through exerkines and gut microbiomes.In this review,we summarized and discussed the latest progress and future development of the above mechanisms for providing a theoretical basis and ideas for the prevention and treatment of sarcopenia.

关 键 词：Skeletal muscle SARCOPENIA EXERCISE Diet Exerkines Signaling pathway Satellite cells 

分 类 号：R151[医药卫生—营养与食品卫生学]