童年创伤影响社交焦虑障碍的心理与生物机制研究进展  

Research progress of psychological and biological mechanism of childhood trauma affecting social anxiety disorder

作　　者：刘益彤 严舒雅 孙靖延 钟舒明[1] 贾艳滨[1] LIU Yitong;YAN Shuya;SUN Jingyan;ZHONG Shuming;JIA Yanbin(The First Affiliated Hospital of Jinan University,Guangzhou 510630,China)

机构地区：[1]暨南大学附属第一医院精神医学科,广州510630 [2]暨南大学管理学院

出　　处：《中国神经精神疾病杂志》2024年第9期565-569,共5页Chinese Journal of Nervous and Mental Diseases

基　　金：国家自然科学基金项目(编号:82271564);国家重点研发计划“先进计算与新兴软件”重点专项(编号:2022YFB4500600);广东省医学科学技术研究基金项目(编号:A2023137)。

摘　　要：社交焦虑障碍(social anxiety disorder,SAD)对个体的社会交往和正常生活具有显著负面影响,而童年创伤在SAD的发生发展中起着重要作用。童年创伤通过影响自我意识的发展,损害信息加工能力,阻碍前额叶-边缘系统环路和默认网络的正常发育,造成糖皮质激素和催产素的分泌异常等,导致个体在正确理解社交线索、合理调控情绪等方面存在困难,在社交情境中无法产生适应性情绪和行为反应,进而可能产生SAD。总之,童年创伤从心理和生理两个方面对社交功能产生持久的不良影响。Social anxiety disorder has a significant negative impact on individuals’social interaction and normal life,and childhood trauma plays an important role in the occurrence and development of SAD.Childhood trauma affects the development of self-awareness,impairs the ability of information processing,hinders the normal development of prefrontal cortex-limbic system loop and default mode network,and causes abnormal secretion of glucocorticoid and oxytocin,which leads to individuals’inability to correctly understand social clues and reasonably regulate emotions,and thus unable to produce adaptive emotional and behavioral responses in social situations,which may lead to SAD.In conclusion,childhood trauma has a lasting adverse effect on social function from both psychological and physiological aspects.

关 键 词：童年创伤 社交焦虑障碍 自我概念 自我关怀 面部表情 心理理论 脑影像 默认网络 内分泌激素 

分 类 号：R749.72[医药卫生—神经病学与精神病学]