Oxytocinergic Control of a Hypothalamic Social Fear Circuitry  

作　　者：Junqiang Zheng Xingying Wu Han Xu 

机构地区：[1]Department of Neurobiology and Department of Psychiatry of the Second Affiliated Hospital and School of Brain Science and Brain Medicine,Zhejiang University School of Medicine,Hangzhou,310058,China [2]Nanhu Brain-Computer Interface Institute,Hangzhou,311100,China [3]Liangzhu Laboratory,MOE Frontier Science Center for Brain Science and Brain-Machine Integration,State Key Laboratory of Brain-Machine Intelligence,Zhejiang University,Hangzhou,311121,China [4]NHC and CAMS Key Laboratory of Medical Neurobiology,Zhejiang University,Hangzhou,310058,China [5]Lingang Laboratory,Shanghai,200031,China

出　　处：《Neuroscience Bulletin》2024年第9期1399-1401,共3页神经科学通报（英文版）

基　　金：National Natural Science Foundation of China(32125018 and 32071005);Zhejiang Provincial Natural Science Foundation of China(LD24H090002);National Key Research and Development Program of China(2021YFA1101701);Non-profit Central Research Institute Fund of Chinese Academy of Medical Sciences(2023-PT310-01);Nanhu Brain-computer Interface Institute(010904008);MOE Frontiers Science Center for Brain Science&Brain-Machine Integration of Zhejiang University.

摘　　要：Exhibiting appropriate social behavior toward conspecifics is crucial for survival within a social group.For instance,after a conflict,it is essential for the loser to stay away from the victor to avoid further harm[1].Previous studies have indicated that the anterior ventrolateral part of the ventromedial hypothalamus(aVMHvl)plays a pivotal role in social fear and avoidance following a social defeat.However,the precise mechanisms through which the aVMHvl effectively transforms social defeat to subsequent behavioral changes in social interaction remain largely unknown.

关 键 词：MEDIAL HYPOTHALAMUS PRECISE 

分 类 号：R741[医药卫生—神经病学与精神病学]