Metabolic reprogramming in skeletal cell differentiation  

作　　者：Joshua C.Bertels Guangxu He Fanxin Long 

机构地区：[1]Department of Surgery,Translational Research Program in Pediatric Orthopedics,The Children’s Hospital of Philadelphia,Philadelphia,PA,USA [2]Department of Orthopedics,The Second Xiangya Hospital,Changsha,Hunan,China [3]Department of Orthopedic Surgery,University of Pennsylvania,Philadelphia,PA,USA

出　　处：《Bone Research》2024年第3期539-554,共16页骨研究（英文版）

基　　金：partly supported by NIH grant R01DK125498 (FL)。

摘　　要：The human skeleton is a multifunctional organ made up of multiple cell types working in concert to maintain bone and mineral homeostasis and to perform critical mechanical and endocrine functions.From the beginning steps of chondrogenesis that prefigures most of the skeleton,to the rapid bone accrual during skeletal growth,followed by bone remodeling of the mature skeleton,cell differentiation is integral to skeletal health.

关 键 词：FUNCTIONS SKELETON PROGRAMMING 

分 类 号：R329.2[医药卫生—人体解剖和组织胚胎学]