人参皂苷CK的制备方法及生理活性研究进展  

Research Progress on Preparation Methods and Physiological Activity of Ginsenoside Compound K

作　　者：宿胜男 田柬昕 钟碧銮 张宇 杜冰[3] SU Shengnan;TIAN Jianxin;ZHONG Biluan;ZHANG Yu;DU Bing(Guangdong Genuine Nutrition Life Technology Co.Limited,Guangzhou 510000;Zhenguan Herbal Prescription EfficacyResearch Center,Guangzhou 510000;College of Food,South China Agricultural University,Guangzhou 510642)

机构地区：[1]广东循证滋补生命科技有限公司,广州510000 [2]贞观草本组方功效研究中心,广州510000 [3]华南农业大学食品学院,广州510642

出　　处：《食品工业》2024年第10期253-259,共7页The Food Industry

基　　金：财政部和农业农村部:国家现代农业产业技术体系(CARS-21)。

摘　　要：人参皂苷CK(ginsenoside compound K,GCK)是人参中的一种非天然存在的稀有二醇型人参皂苷,可由人参皂苷Rb1、Rb2、Rc等二醇型人参皂苷在人体肠道内通过生物转化而成。研究发现,GCK具有保护肝肾、抗炎、镇痛、抗疲劳、抗肿瘤等多种活性作用,需大量制备以满足医疗和科研等方面的需求,可通过微生物、酶等生物转化方法制备GCK。就GCK的生物转化方法及生理作用进行系统的综述,旨在为GCK的制备和及相关应用研究提供依据。Ginsenoside compound K is a rare ginsenoside that does not exist naturally in ginseng.It can be biotransformed from ginsenoside Rb1,Rb2,Rc and other ginsenosides in human intestine.The studies have found that ginsenoside compound K has many pharmacological effects such as protecting liver and kidney,anti-inflammatory,analgesic,anti fatigue and anti-tumor,etc.It needs to be prepared in large quantities to meet the needs of medical and scientific research.Ginsenoside compound K can be prepared by biological transformation methods such as microorganisms and enzymes.The biotransformation methods and pharmacological effects of ginsenoside compound K are systematically reviewed in order to provide a basis for the preparation and application of ginsenoside compound K.

关 键 词：人参 人参皂苷CK 微生物转化法 酶转化法 生物合成法 生理活性 

分 类 号：TS201.4[轻工技术与工程—食品科学]