后生元的概念及其应用进展  

The concept of postbiotics and its applications updates

作　　者：陈坚[1] 张会禄[1] 邱志兵[1] 潘亦达 CHEN Jian;ZHANG Huilu;QIU Zhibing;PAN Yida(Department of Gastroenterology,Huashan Hospital,Fudan University,Shanghai 200040,China)

机构地区：[1]复旦大学附属华山医院消化内科,上海200040

出　　处：《上海医药》2024年第19期16-21,共6页Shanghai Medical & Pharmaceutical Journal

摘　　要：后生元(postbiotics)是一个与益生菌相关的新概念,是指特定的灭活微生物或其无菌提取物,它能通过与益生菌不同的生物学特性为宿主的健康提供益处。体内外研究表明,一些后生元具有抗炎、免疫调节、抗氧化和抗菌活性,具有用于代谢综合征、焦虑症、抑郁症甚至新型冠状病毒感染辅助治疗的潜力,尽管相关作用机制和所涉信号通路尚未完全阐明。随着对后生元研究与开发的日益深入,后生元有望在健康食品行业和医疗保健领域得到广泛的应用。In recent years,postbiotics,a new concept related to probiotics,has been used to describe some certain inactivated microorganisms or sterile extracts,which may provide host health benefits through distinct biological activities from those of probiotics.A series of studies have shown that some postbiotics have anti-inflammatory,immunomodulatory,antioxidant and antibacterial activities,which have been used in the adjuvant treatment of metabolic syndrome,anxiety,depression,and even corona virus disease 2019,although their mechanisms and the signaling pathways involved have not been fully elucidated.With the deepening of the research and development of postbiotics,it is expected to be widely used in the healthy food industry and medical health care field in the future.

关 键 词：益生菌 后生元 益生元 合生元 肠道菌群 

分 类 号：TS202.3[轻工技术与工程—食品科学]