Next-generation research on transcriptional regulation of plant immunity  

作　　者：Akira Mine 

机构地区：[1]Laboratory of Plant Pathology,Graduate School of Agriculture,Kyoto University,Kyoto 606-8502,Japan

出　　处：《Molecular Plant》2024年第11期1651-1653,共3页分子植物（英文版）

基　　金：supported by the Grant-in-Aid for Scientific Research(B)(24K01757);the Grant-in-Aid for Challenging Exploratory Research(22K19178).

摘　　要：Plant health is fundamental for agricultural production to feed the growing global population as well as for primary production to sustain ecosystem functions.The innate immune system of plants is integral to their health;it is activated upon recognition of pathogen invasion by immune receptors,leading to pathogen resistance through genome-wide transcriptional regulation.This defense-associated transcriptome reprogramming is mediated by various immune signals,including the phytohormone salicylic acid(SA).SA plays a pivotal role in activating pathogen resistance both locally in infected tissues and systemically in uninfected tissues.In Arabidopsis thaliana,SA is perceived by its receptors NONEXPRESSOR OF PATHOGENESIS-RELATED GENES 1(NPR1),NPR3,and NPR4.While NPR3 and NPR4 function as negative regulators of SA signaling,NPR1 serves as a key positive regulator of SA-mediated transcriptomic changes and pathogen resistance(Ding et al.,2018).Consistent with its lack of a DNA-binding domain,NPR1 has been shown to act as a transcription cofactor for multiple transcription factors(TFs)such as TGAs and WRKYs(Wang et al.,2006;Kumar et al.,2022).Besides TFs,other components of the transcriptional machinery are likely to participate in NPR1-regulated transcriptional responses,as NPR1 forms nuclear condensates upon SA induction(Zavaliev et al.,2020).Despite decades of research on NPR1’s functions in plant immunity,a comprehensive understanding of how NPR1 cooperates with multiple TFs and other components of the transcriptional machinery to initiate and propagate transcriptional responses to SA is still lacking.

关 键 词：TRANSCRIPTIONAL plant IMMUNITY 

分 类 号：Q94[生物学—植物学]