Biochemical dissection of STAT3 signaling in amyotrophic lateral sclerosis  

作　　者：Savina Apolloni Nadia D’Ambrosi 

机构地区：[1]Department of Biology,University of Rome Tor Vergata,Rome,Italy

出　　处：《Neural Regeneration Research》2025年第11期3229-3230,共2页中国神经再生研究（英文版）

基　　金：funded by Fondazione AriSLA ETS(Fondazione di ricerca per la SLA ETS),ReNicALS project to SA;supported by#NEXTGENERATIONEU(NGEU)and funded by the Ministry of University and Research(MUR),National Recovery and Resilience Plan(NRRP),project MNESYS(PE0000006)-A Multiscale Integrated Approach to the Study of the Nervous System in Health and Disease(DN.1553 October 11,2022)。

摘　　要：Amyotrophic lateral sclerosis(ALS)is a progressive neurodegenerative disease characterized by the loss of upper and lower motor neurons,clinically marked by muscle atrophy and weakness.Although the clinical course is highly variable,the average time from the onset of symptoms to the need for respiratory support or death is 3-5 years.ALS is the most prevalent motor neuron disease in adults,occurring at a rate of 2 per 100,000 individuals and affecting 5.4 per 100,000 individuals overall.

关 键 词：STAT3 DISSECTION SCLEROSIS 

分 类 号：R744.8[医药卫生—神经病学与精神病学]