香椿抑菌复合水凝胶的制备及其性能  

Preparation and Properties of Bacteriostatic Compound Hydrogels based on Toona Sinensis

作　　者：席圣景 何承阳 彭必章 崔新瑶 秦文[1] 刘书香[1] XI Shengjing;HE Chengyang;PENG Bizhang;CUI Xinyao;QIN Wen;LIU Shuxiang(College of Food Science,Sichuan Agricultural University,Ya an 625014,China)

机构地区：[1]四川农业大学食品学院,四川雅安625014

出　　处：《塑料工业》2024年第11期150-158,共9页China Plastics Industry

基　　金：2023年省级大学生创新创业训练计划(S202310626098)。

摘　　要：本研究旨在对香椿活性物抑菌能力进行准确的量化,基于提取的抑菌物质,通过胶束自由基聚合策略开发一款高力学性能和多功能性的超分子有机凝胶半互穿结构香椿水凝胶(AGE-Toona),并确定凝胶的相关特性及抑菌能力。对提纯所需的大孔树脂进行筛选并利用滤纸片法对香椿活性物质抑菌性能进行测定。将香椿生物活性物质与丙烯酰胺、十二烷基苯磺酸钠、甲基丙烯酸月桂酯、明胶等结合形成目标产物,并对其部分表征(如力学性能、溶胀性、抑菌性等)进行测定以评估此产品是否具有良好的应用性。研究结果显示,AB-8大孔树脂纯化效果更佳,其纯化组分对致病性大肠杆菌和金黄色葡萄球菌有优良抑菌效果,抑菌圈直径分别为11.51、11.25 mm。同时,合成的有机凝胶展示出优秀的综合性能,其拥有较好的力学强度(拉伸强度约0.4 MPa,压缩强度4.1 MPa)、超可拉伸(断裂伸长率约1324%),高溶胀度(823.3%)和良好抑菌作用,对于金黄色葡萄球菌有明显的抑菌作用。利用这些优势,AGE-Toona水凝胶可能在医疗抑菌敷料得到合适应用。The aim of this study is to accurately quantify the antibacterial activity of Toona sinensis active substances.Based on the antibacterial substance extracted,a kind of supramolecular organic Toona sinensis hydrogel(AGE-Toona)with a semi-interpenetrating structure,high mechanical properties and multi-functionality was developed through the micellar radical polymerization strategy.The relevant properties and antibacterial activity of the gel were determined.The macroporous resins needed for purification were screened and the bacteriostatic properties of the Toona sinensis active substances were determined by filter paper method.The Toona sinensis bioactive substances were combined with acrylamide,sodium dodecylbenzene sulfonate,lauryl methacrylate and gelatin to form the target products.Partial characteristics such as mechanical properties,swelling properties and antibacterial properties were measured to evaluate whether the products have good applications.The results show that AB-8 macroporous resin has better purification effect,and the purified components have an excellent antibacterial effect on pathogenic Escherichia coli and staphylococcus aureus,and the corresponding antibacterial zone diameters are respectively 11.51 and 11.25 mm.At the same time,the synthetic organogel shows excellent comprehensive properties.It has good strength(a tensile strength of about 0.4 MPa,a compression strength of about 4.1 MPa),super stretchability(about 1324%),high swelling degree(823.3%)and good bacteriostasis(especially for staphylococcus aureus).Taking these advantages,AGE-Toona hydrogel might find suitable applications in the medical antibacterial dressings.

关 键 词：香椿 植物源抑菌物质 物质分析 抑菌水凝胶 

分 类 号：TQ316.322[化学工程—高聚物工业]