De novo biosynthesis of phytohormone jasmonates in engineered yeast  

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作  者:Chengfeng Xue Meng Zhang Ruifeng Yao 

机构地区:[1]State Key Laboratory of Chemo/Biosensing and Chemometrics,Hunan Provincial Key Laboratory of Plant Functional Genomics and Developmental Regulation,College of Biology,Hunan University,Changsha,410082,China [2]Greater Bay Area Institute for Innovation,Hunan University,Guangzhou,511300,China [3]Shenzhen Research Institute,Hunan University,Shenzhen,518000,China

出  处:《Advanced Agrochem》2024年第1期4-5,共2页现代农业化学(英文)

基  金:the support from the National Key Research and Development Program of China(Nos.2021YFA1300400 and 2022YFF1002000);Shenzhen Science and Technology Innovation Commission(No.2021Szvup037);the Natural Science Foundation of Hunan Province(Nos.2022RC1015 and 2023RC1050).

摘  要:The plant defense hormone jasmonates not only play important roles in plant growth,development,and resistance,but also hold promise for bringing new strategies in plant protection and cancer therapy.Recently,de novo biosynthesis of natural and unnatural jasmonates in refactored yeast with integration of 15 heterologous genes and 3 native genes deleted was reported.Here,we highlight the feasible and sustainable platform to efficiently produce jasmonates,which would benefit both agriculture and human health.

关 键 词:Plant hormone JASMONATE de novo synthesis YEAST 

分 类 号:R73[医药卫生—肿瘤]

 

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