Effect of bright-light therapy on depression and anxiety of a patient with Alzheimer’s disease combined with sleep disorder:A case report  

作　　者：Xi Mei Chen-Jun Zou Cheng-Ying Zheng Jun Hu Dong-Sheng Zhou 

机构地区：[1]Department of Psychiatry,Affiliated Kangning Hospital of Ningbo University,Ningbo 315211,Zhejiang Province,China [2]Department of Geriatric,Ningbo Kangning Hospital,Ningbo 315201,Zhejiang Province,China [3]Key Lab,Ningbo Kangning Hospital,Ningbo 315201,Zhejiang Province,China

出　　处：《World Journal of Psychiatry》2024年第12期1982-1987,共6页世界精神病学杂志（英文）

摘　　要：BACKGROUND Alzheimer’s disease(AD)is a common type of dementia due to neuronal impairment.In addition,psychobehavioral symptoms including severe sleep disorders,depression and anxiety can occur in most patients with AD.CASE SUMMARY We report a case of a 68-year-old woman with a 2-year history of AD.She initially presented with memory loss,progressively more severe,leading to a depressive and anxious status.The clinical symptoms also included severe sleep disturbances.Considering the age and health state of the patient,a non-pharmacological treatment of bright light therapy was used to improve her sleep quality.The treatment was provided for 30 minutes twice a day,during 8:30 am to 9:00 am and 16:30 pm to 17:00 pm.After 4 weeks of therapy,the sleep quality notably improved,with a marked decrease in daytime sleep,increase in nighttime sleep,and disappearance of nocturnal activity.The depression and anxiety were also suppressed significantly.CONCLUSION This case report suggested that bright light therapy can have a positive effect on sleep quality in elderly patients with AD and can be used as an effective and safe non-pharmacological treatment.

关 键 词：Bright-light therapy Sleep disturbance Alzheimer’s disease DEMENTIA Nonpharmacological treatment Case report 

分 类 号：R749.16[医药卫生—神经病学与精神病学]